National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China; Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Environ Int. 2019 Mar;124:493-500. doi: 10.1016/j.envint.2019.01.045. Epub 2019 Jan 24.
Several epidemiological studies have shown that blood pressure changes with temperature based on the daily temperature and linear relationship assumption. However, little is known about the true curve shape of the relationship between temperature and blood pressure.
The objective of this study was to investigate the non-linear relationship between hourly temperature and blood pressure.
This is a prospective panel study comprising 100 participants in Suzhou, China. The blood pressure of each participant was measured >50 times between October 2013 and January 2016. Hourly temperature data were derived from the nearest monitoring station owned by the China Meteorological Administration. A Distributed Lag Nonlinear Model (DLNM) was used to investigate the relationship between hourly temperature and blood pressure.
We found that the relationship between hourly temperature and blood pressure was parabolic. Short-term exposure to hourly temperatures had significant cold and heat effects on systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and mean arterial pressure (MAP). The hourly temperature had a significant lag effect on blood pressure, with a lag time of 0-5 h. Alcohol users were more sensitive to the cold effects of hourly temperature, and the diabetic population was more sensitive to the heat effects of hourly temperature on PP.
Temperature imparts short-term effects on blood pressure. Therefore, timely protective measures during cold waves or cold weather are beneficial to maintain stable blood pressure levels to reduce the risk of blood pressure related diseases.
多项流行病学研究表明，血压会随每日气温变化，且两者呈线性关系。然而，关于气温与血压之间真实关系的曲线形状，我们知之甚少。
本研究旨在探究血压与气温之间的非线性关系。
这是一项在中国苏州开展的前瞻性队列研究，共纳入 100 名参与者。2013 年 10 月至 2016 年 1 月期间，对每位参与者的血压进行了>50 次测量。从中国气象局拥有的最近的监测站获取每小时的气温数据。采用分布滞后非线性模型（DLNM）来探究每小时气温与血压之间的关系。
我们发现，每小时气温与血压之间的关系呈抛物线形。短期暴露于每小时气温对收缩压（SBP）、舒张压（DBP）、脉压（PP）和平均动脉压（MAP）均有显著的冷、热效应。每小时气温对血压具有显著的滞后效应，滞后时间为 0-5 小时。饮酒者对每小时气温的寒冷效应更为敏感，而糖尿病患者对每小时气温升高对 PP 的影响更为敏感。
气温对血压具有短期影响。因此，在寒潮或寒冷天气期间采取及时的保护措施有利于维持血压稳定，降低与血压相关疾病的风险。
