2018年自身免疫性肝病的研究进展

[Research advances of autoimmune liver diseases in 2018].

作者信息

Chen Y, Wang Q X, Ma X

机构信息

Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University School of Medicine;Institute of Digestive Disease, Shanghai 200001, China.

出版信息

Zhonghua Gan Zang Bing Za Zhi. 2019 Jan 20;27(1):14-17. doi: 10.3760/cma.j.issn.1007-3418.2019.01.005.

DOI:10.3760/cma.j.issn.1007-3418.2019.01.005

PMID:30685918

Abstract

Autoimmune liver disease is a group of hepatobiliary injuries mediated by abnormal immunity. It mainly includes autoimmune hepatitis, primary biliary cholangitis and primary sclerosing cholangitis. Recently, an advancement of diagnostic technology has improved the detection and treatment of autoimmune hepatitis. However, it is easy to be confused with other liver diseases. Thus, the standardization of diagnosis and treatment of autoimmune liver diseases has become a main concern. Moreover, new progress has been made in basic research and clinical treatment of autoimmune liver diseases since 2018. In this review, we have introduced the latest research advances for the diagnosis and treatment of autoimmune liver diseases.

摘要

自身免疫性肝病是一组由异常免疫介导的肝胆损伤。它主要包括自身免疫性肝炎、原发性胆汁性胆管炎和原发性硬化性胆管炎。近年来，诊断技术的进步提高了自身免疫性肝炎的检测和治疗水平。然而，它很容易与其他肝病相混淆。因此，自身免疫性肝病诊断和治疗的标准化已成为主要关注点。此外，自2018年以来，自身免疫性肝病的基础研究和临床治疗取得了新进展。在这篇综述中，我们介绍了自身免疫性肝病诊断和治疗的最新研究进展。