Division of Aging and Geriatric Dentistry, Department of Oral Function and Morphology, Tohoku University Graduate School of Dentistry.
Japanese Red Cross Ishinomaki Hospital.
J Epidemiol. 2020 Feb 5;30(2):84-90. doi: 10.2188/jea.JE20180203. Epub 2019 Jan 26.
A growing number of epidemiology studies have shown that poor oral health is associated with an increased incidence of functional disability. However, there are few studies in which the confounding bias is adjusted appropriately. In this study, we examined whether dental status is associated with functional disability in elderly Japanese using a 13-year prospective cohort study after elimination of confounding factors with propensity score matching.
Participants were community-dwelling Japanese aged 70 years or older who lived in the Tsurugaya district of Sendai (n = 838). The number of remaining teeth (over 20 teeth vs 0-19 teeth) was defined as the exposure variable. The outcome was the incidence of functional disability, defined as the first certification of long-term care insurance (LTCI) in Japan. The variables that were used to determine propensity score matching were age, sex, body mass index (BMI), medical history (stroke, hypertension, myocardial infarction, cancer, and diabetes), smoking, alcohol consumption, educational attainment, depression symptoms, cognitive impairment, physical function, social support, and marital status.
As a result of the propensity score matching, 574 participants were selected. Participants with 0-19 teeth were more likely to develop functional disability than those with 20 or more teeth (hazard ratio 1.33; 95% confidence interval, 1.01-1.75).
In this prospective cohort study targeting community-dwelling older adults in Japan, having less than 20 teeth was confirmed to be an independent risk factor for functional disability even after conducting propensity score matching. This study supports previous publications showing that oral health is associated with functional disability.
越来越多的流行病学研究表明,口腔健康状况不佳与功能障碍的发生率增加有关。然而,在适当调整混杂偏差的研究中,这种情况很少见。在这项研究中,我们通过倾向评分匹配消除混杂因素后,使用一项为期 13 年的前瞻性队列研究,检验了牙齿状况与日本老年人功能障碍之间的关系。
参与者为居住在仙台鹤谷地区的 70 岁或以上的社区居民日本(n=838)。将剩余牙齿数(超过 20 颗牙齿与 0-19 颗牙齿)定义为暴露变量。结果是功能障碍的发生率,定义为首次获得日本长期护理保险(LTCI)的认证。用于确定倾向评分匹配的变量包括年龄、性别、体重指数(BMI)、病史(中风、高血压、心肌梗死、癌症和糖尿病)、吸烟、饮酒、教育程度、抑郁症状、认知障碍、身体功能、社会支持和婚姻状况。
通过倾向评分匹配,选择了 574 名参与者。与拥有 20 颗或更多牙齿的参与者相比,拥有 0-19 颗牙齿的参与者更有可能出现功能障碍(风险比 1.33;95%置信区间,1.01-1.75)。
在这项针对日本社区居住的老年人的前瞻性队列研究中,即使进行了倾向评分匹配,也证实了拥有少于 20 颗牙齿是功能障碍的独立危险因素。这项研究支持了先前的研究结果,表明口腔健康与功能障碍有关。