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自身免疫性获得性血友病继发自发性脊髓硬膜外血肿

Spontaneous Spinal Epidural Haematoma Secondary to Autoimmune Acquired Haemophilia.

作者信息

Afshari Fardad T, Parikh Dhruv, Petrik Vladimir

机构信息

Department of Neurosurgery, Birmingham University Hospital, Birmingham, United Kingdom.

出版信息

Case Rep Neurol. 2018 Dec 13;10(3):353-356. doi: 10.1159/000495028. eCollection 2018 Sep-Dec.

Abstract

Spontaneous spinal epidural haematoma is a rare entity associated with high morbidity. Although there are previous reports of spinal haematoma secondary to X-linked genetic haemophilia, there are no such cases secondary to acquired autoimmune haemophilia. We report the case of a 71-year-old patient who presented with sudden quadriplegia secondary to cervical (C2 to T1) epidural haematoma as a result of undiagnosed autoimmune acquired haemophilia A. She underwent emergency cervical laminectomy and evacuation of spinal haematoma with significant recovery in upper limb function. This case highlights the importance of haematological investigations in patients with spontaneous spinal haematoma.

摘要

自发性脊髓硬膜外血肿是一种罕见的疾病,发病率很高。虽然之前有关于X连锁遗传性血友病继发脊髓血肿的报道,但尚无获得性自身免疫性血友病继发此类病例的报道。我们报告一例71岁患者,因未确诊的获得性自身免疫性A型血友病导致颈椎(C2至T1)硬膜外血肿,出现突发四肢瘫痪。她接受了急诊颈椎椎板切除术并清除脊髓血肿,上肢功能有显著恢复。该病例强调了对自发性脊髓血肿患者进行血液学检查的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/788d/6341357/daaf2f41aba6/crn-0010-0353-g01.jpg

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