Cholesterol pathway the Achilles heel in prostate cancer metastasis.
作者信息
Heidegger Isabel, Pichler Renate, Pircher Andreas
机构信息
Department of Urology, Hematology and Oncology, Medical University Innsbruck, Innsbruck, Austria.
Department of Internal Medicine V, Hematology and Oncology, Medical University Innsbruck, Innsbruck, Austria.
出版信息
Transl Androl Urol. 2018 Dec;7(Suppl 6):S686-S687. doi: 10.21037/tau.2018.08.12.
Abstract
摘要
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Transl Androl Urol. 2018 Dec;7(Suppl 6):S686-S687. doi: 10.21037/tau.2018.08.12.
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本文引用的文献
1
Prostate Cancer Metastasis - Fueled by Fat?前列腺癌转移——由脂肪驱动？
N Engl J Med. 2018 Apr 26;378(17):1643-1645. doi: 10.1056/NEJMcibr1800808.
2
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.异常的 SREBP 依赖性脂肪生成程序促进转移性前列腺癌。
Nat Genet. 2018 Feb;50(2):206-218. doi: 10.1038/s41588-017-0027-2. Epub 2018 Jan 15.
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Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities.癌症临床代谢谱研究的Meta分析：挑战与机遇
EMBO Mol Med. 2016 Oct 4;8(10):1134-1142. doi: 10.15252/emmm.201606798. Print 2016 Oct.
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Subgroups of Castration-resistant Prostate Cancer Bone Metastases Defined Through an Inverse Relationship Between Androgen Receptor Activity and Immune Response.通过雄激素受体活性和免疫反应之间的反比关系定义去势抵抗性前列腺癌骨转移的亚群。
Eur Urol. 2017 May;71(5):776-787. doi: 10.1016/j.eururo.2016.07.033. Epub 2016 Aug 3.
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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.代谢组学图谱揭示了肌氨酸在前列腺癌进展中的潜在作用。
Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762.
6
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.固醇调节元件结合蛋白：肝脏中胆固醇和脂肪酸合成完整程序的激活剂。
J Clin Invest. 2002 May;109(9):1125-31. doi: 10.1172/JCI15593.
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