Viotto Guilherme, Paim Leonardo, Souza Renato, Aprígio Joaquim, Lacerda Lucas, Pomerantzeff Pablo, Jatene Marcelo B, Palma José Honório, Jatene Fabio B
Cardiopneumology Department, InCor-Heart Institute of the University of São Paulo Clinic's Hospital, São Paulo, Brazil.
Interact Cardiovasc Thorac Surg. 2019 Jul 1;29(1):59-63. doi: 10.1093/icvts/ivy362.
In this study, we sought to evaluate early outcomes of transcatheter valve-in-valve implantation in patients with a degenerated bioprosthesis in the tricuspid position.
We used a prospective study, which included patients with a degenerated bioprosthesis in the tricuspid position who were considered high-risk by our heart team and who underwent a valve-in-valve implantation. The procedures were performed via transjugular venous access and were done with the patient under general anaesthesia with transoesophageal echocardiographic and fluoroscopic guidance. Perioperative data were analysed, and the patients were followed prospectively.
Seven patients were included. The baseline diagnoses were 3 patients with Ebstein's anomaly, 1 patient with tetralogy of Fallot, 1 patient with neonatal endocarditis, 1 patient with ventricular septal defect with a double tricuspid lesion and 1 patient with rheumatic mitral and tricuspid valve who underwent a combined transapical mitral and transjugular tricuspid valve-in-valve implantation. The mean age was 33 ± 10.8 years and 57.1% of the patients were men. The mean number of previous thoracotomies was 3 ± 2 (range 1-5) procedures. The mean follow-up was 1.24 years. The implant was successful in all cases, and there was no need for conversion to open surgery. There were no deaths during the study period, and all patients are currently in the New York Heart Association functional class I/II. There was a statistically significant difference when the mean transvalvular gradients preimplantation and postimplantation were compared (P < 0.001).
Percutaneous tricuspid valve implantation should be considered a safe and effective therapy and stands as a viable, reliable alternative for the treatment of a degenerated bioprosthesis in high-surgical-risk/inoperable patients.
在本研究中,我们试图评估三尖瓣位生物瓣衰败患者经导管瓣中瓣植入术的早期疗效。
我们采用前瞻性研究,纳入三尖瓣位生物瓣衰败且心脏团队认为属于高风险并接受瓣中瓣植入术的患者。手术经颈静脉入路,在全身麻醉下、经食管超声心动图和荧光透视引导下进行。分析围手术期数据,并对患者进行前瞻性随访。
共纳入7例患者。基线诊断为:3例埃布斯坦畸形、1例法洛四联症、1例新生儿心内膜炎、1例室间隔缺损合并双三尖瓣病变以及1例风湿性二尖瓣和三尖瓣病变患者,后者接受了经心尖二尖瓣和经颈静脉三尖瓣瓣中瓣联合植入术。平均年龄为33±10.8岁,57.1%的患者为男性。既往开胸手术的平均次数为3±2次(范围1 - 5次)。平均随访时间为1.24年。所有病例植入均成功,无需转为开放手术。研究期间无死亡病例,所有患者目前纽约心脏协会心功能分级为I/II级。比较植入前和植入后的平均跨瓣压差有统计学显著差异(P < 0.001)。
经皮三尖瓣植入术应被视为一种安全有效的治疗方法,是高手术风险/无法手术患者生物瓣衰败治疗的可行、可靠替代方案。