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[儿童多发性肌炎和皮肌炎]

[Polymyositis and dermatomyositis in childhood].

作者信息

Rodríguez Núñez A, Fernández Bustillo J M, Rodríguez Pérez E, Novo Rodríguez I, Pérez Becerra E, Peña Guitián J, Castro Gago M

机构信息

Departamento de Pediatría, Hospital General de Galicia, Facultad de Medicina, Universidad de Santiago de Conpostela.

出版信息

An Esp Pediatr. 1988 Oct;29(4):288-92.

PMID:3069018
Abstract

Authors report clinical and laboratory findings, treatment and evolution of six girls and three boys aged between 20 months and 13 years, diagnosed of juvenile polymyositis-dermatomyositis in the last seven years. Presenting symptoms were asthenia and proximal muscle weakness; in 3 cases characteristic skin lesions were associated. All were treated initially with prednisone p.o. (1-2 mg/kg/day) response being favourable in seven. Two patients with chronic evolution were treated with methotrexate and IV bolus of methylprednisolone.

摘要

作者报告了在过去七年中诊断为幼年型多发性肌炎-皮肌炎的6名女孩和3名男孩(年龄在20个月至13岁之间)的临床和实验室检查结果、治疗及病情进展情况。主要症状为乏力和近端肌无力;3例伴有特征性皮肤损害。所有患者最初均口服泼尼松(1-2mg/kg/天),7例反应良好。2例病情呈慢性进展的患者接受了甲氨蝶呤和静脉推注甲基泼尼松龙治疗。

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