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局部应用荧光素对荧光单克隆抗体在衣原体性结膜炎诊断中的影响。

The effect of topically applied fluorescein on fluorescent monoclonal antibodies in the diagnosis of chlamydial conjunctivitis.

作者信息

Vrabec M P, McCanna P J

机构信息

Department of Ophthalmology, University of Wisconsin Medical School, Madison.

出版信息

Ann Ophthalmol. 1988 Nov;20(11):421-3.

PMID:3069022
Abstract

Fluorescein-conjugated monoclonal antibodies have now been developed for use in the diagnosis of chlamydial conjunctivitis. This article discusses a clinical trial involving the use of such antibodies. We found that topical application of fluorescein before obtaining a specimen did not result in a statistically significant rate of false positives in a control group of patients.

摘要

现在已经开发出了用于诊断衣原体性结膜炎的荧光素结合单克隆抗体。本文讨论了一项涉及使用此类抗体的临床试验。我们发现,在对照组患者中,在获取标本前局部应用荧光素并未导致具有统计学意义的假阳性率。

相似文献

1
The effect of topically applied fluorescein on fluorescent monoclonal antibodies in the diagnosis of chlamydial conjunctivitis.局部应用荧光素对荧光单克隆抗体在衣原体性结膜炎诊断中的影响。
Ann Ophthalmol. 1988 Nov;20(11):421-3.
2
Direct fluorescent monoclonal antibody stain for rapid detection of infant Chlamydia trachomatis infections.用于快速检测婴儿沙眼衣原体感染的直接荧光单克隆抗体染色法。
Pediatrics. 1984 Aug;74(2):224-8.
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Rapid diagnosis of Chlamydia trachomatis infections by a monoclonal antibody direct immunofluorescence test.
J Trop Med Hyg. 1987 Dec;90(6):307-10.
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Detection of Chlamydia trachomatis in the female genital tract by fluorescein-labelled monoclonal antibody.用荧光素标记的单克隆抗体检测女性生殖道中的沙眼衣原体。
Acta Microbiol Hung. 1987;34(1):93-6.
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[Direct identification of Chlamydia trachomatis using fluorescent monoclonal antibodies in infections of the lower urogenital tract].
Ann Dermatol Venereol. 1986;113(9):799-803.
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An application of fluorescein-conjugated monoclonal antibodies to the diagnosis of Chlamydia trachomatis infection in children.荧光素偶联单克隆抗体在儿童沙眼衣原体感染诊断中的应用。
Tohoku J Exp Med. 1985 Jan;145(1):57-63. doi: 10.1620/tjem.145.57.
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Use of monoclonal antibodies in the diagnosis of chlamydial urethritis and cervicitis.
Dev Biol Stand. 1984;57:125-8.
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[Evaluation of sensitivity and specificity of 3 reagents of direct immunofluorescence in the diagnosis of Chlamydia trachomatis].
Ginecol Obstet Mex. 1994 Nov;62:368-73.
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[Direct diagnosis of Chlamydia trachomatis using monoclonal antibodies: diagnosis without culture?].[使用单克隆抗体直接诊断沙眼衣原体:无需培养即可诊断?]
Ned Tijdschr Geneeskd. 1985 Sep 21;129(38):1824-7.
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Fluorescein-conjugated monoclonal antibodies to detect Chlamydia trachomatis in smears.用于检测涂片沙眼衣原体的荧光素偶联单克隆抗体。
Lancet. 1985 Aug 31;2(8453):509. doi: 10.1016/s0140-6736(85)90450-7.

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