一例受益于西格玛-1受体激动剂氟伏沙明的兔综合征报告。
A Report of Rabbit Syndrome Who Benefited from Sigma 1 Agonist Fluvoxamine.
作者信息
Albayrak Yakup, Beyazyüz Murat, Abbak Özlem, Altındağ Ece
机构信息
Department of Psychiatry, Faculty of Medicine, Namık Kemal University, Tekirdag, Turkey.
出版信息
Clin Psychopharmacol Neurosci. 2019 Feb 28;17(1):134-138. doi: 10.9758/cpn.2019.17.1.134.
Abstract
Rabbit Syndrome is an uncommon side effect of antipsychotic treatment. Although it is usually associated with typical antipsychotics, it can also be related to atypical antipsychotics. Anticholinergics are the most accepted treatment approach in treating Rabbit Syndrome. Fluvoxamine is a member of selective serotonin reuptake inhibitors and it is a potent agonist of sigma 1 receptors. In this article, we report a Rabbit Syndrome case who has benefited from fluvoxamine, in terms of both depressive disorder and Rabbit Syndrome; and present the data on the effects of sigma 1 agonist fluvoxamine on numerous movement disorders.
摘要
兔综合征是抗精神病药物治疗罕见的副作用。虽然它通常与典型抗精神病药物有关，但也可能与非典型抗精神病药物有关。抗胆碱能药物是治疗兔综合征最被认可的治疗方法。氟伏沙明是选择性5-羟色胺再摄取抑制剂的一种，是σ1受体的强效激动剂。在本文中，我们报告了1例兔综合征患者，其抑郁症和兔综合征均从氟伏沙明治疗中获益；并展示了σ1激动剂氟伏沙明对多种运动障碍影响的数据。
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