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胸主动脉腔内修复术后晚期开放转换。

Late open conversion after thoracic endovascular aortic repair.

机构信息

Division of Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Republic of Korea.

Division of Radiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Republic of Korea.

出版信息

J Vasc Surg. 2019 Aug;70(2):439-448.e1. doi: 10.1016/j.jvs.2018.11.019. Epub 2019 Jan 26.

Abstract

OBJECTIVE

With the increasing use of endovascular aortic repair, open repair after aortic stent grafting is of increasing interest. We retrospectively reviewed cases of late open conversion for complications after thoracic endovascular aortic repair (TEVAR).

METHODS

TEVAR due to aortic aneurysm and dissection was performed in 538 patients between 1994 and 2017. A total of 33 patients, including 4 patients referred from other centers, required late conversion to open repair; 14 (42.4%) patients required circulatory arrest for aortic arch involvement. The mean interval to open conversion after TEVAR was 33.9 months (range, 1-123 months). Demographics of the patients, reason for conversion, surgical techniques, surgical outcomes, and survival were reviewed.

RESULTS

Indications for late open conversion included type I endoleak (14), stent graft-induced new entry intimal tear (6), retrograde type A dissection (4), stent migration and fracture (3), stent graft infection (3), sac enlargement without endoleak (1), aortopulmonary fistula (1), and stent implantation failure (1). Hospital mortality was 9.1% (3/33). All occurred in the patients with arch involvement. The patients had several major morbidities; six patients (18.1%) had pulmonary complications, two (6.1%) suffered a stroke, one (3.0%) experienced paraplegia, and one (3.0%) had renal failure. Overall survival rates at 1 year, 5 years, and 10 years were 84.5% ± 6.4%, 74.5% ± 8.7%, and 67.1% ± 10.1%, respectively. The arch involvement group (48.1% ± 15.7%) had significantly worse 10-year survival than the no arch involvement group (86.1% ± 9.4%; P = .048).

CONCLUSIONS

Despite the complexity of TEVAR, open conversion due to late complications can be performed successfully with acceptable results. However, cases involving the aortic arch have relatively worse outcomes. Lifelong surveillance is mandatory, and early decision-making about open conversion before the development of a complicated aortic arch lesion is suggested to achieve better outcomes.

摘要

目的

随着血管内主动脉修复术的应用日益增多,胸主动脉腔内修复术(TEVAR)后开放修复术的应用也越来越受到关注。本研究回顾性分析了 TEVAR 后因并发症而进行晚期开放转换的病例。

方法

1994 年至 2017 年间,共有 538 例患者因主动脉瘤和夹层行 TEVAR。共有 33 例患者(包括 4 例来自其他中心的转诊患者)需要进行晚期开放转换,其中 14 例(42.4%)患者因主动脉弓受累需要体外循环停循环。TEVAR 后开放转换的平均时间为 33.9 个月(范围,1-123 个月)。回顾了患者的一般资料、转换原因、手术技术、手术结果和生存率。

结果

晚期开放转换的指征包括Ⅰ型内漏(14 例)、支架移植物引起的新入口内膜撕裂(6 例)、逆行型 A 型夹层(4 例)、支架移位和骨折(3 例)、支架移植物感染(3 例)、无内漏的假腔扩大(1 例)、主肺动脉瘘(1 例)和支架植入失败(1 例)。住院死亡率为 9.1%(3/33)。所有死亡均发生在弓部受累的患者中。这些患者有多种严重的并发症;6 例(18.1%)患者出现肺部并发症,2 例(6.1%)患者发生中风,1 例(3.0%)患者发生截瘫,1 例(3.0%)患者发生肾衰竭。术后 1 年、5 年和 10 年的总体生存率分别为 84.5%±6.4%、74.5%±8.7%和 67.1%±10.1%。弓部受累组(48.1%±15.7%)的 10 年生存率明显低于无弓部受累组(86.1%±9.4%;P=0.048)。

结论

尽管 TEVAR 技术复杂,但晚期并发症所致的开放转换可获得满意的结果。然而,涉及主动脉弓的病例结果相对较差。需要终身监测,建议在复杂的主动脉弓病变发生之前做出开放转换的早期决策,以获得更好的结果。

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