Patel Jitendra N, Donta Ajaykumar B, Patel Arpit C, Pandya Amrish N, Kulkarni Swati S
Department of Immuno-Hematology and Blood Transfusion, Government Medical College and New Civil Hospital, Surat, Gujarat, India.
Department of Transfusion Medicine, ICMR- National Institute of Immunohaematology, Mumbai, Maharashtra, India.
Asian J Transfus Sci. 2018 Jul-Dec;12(2):180-182. doi: 10.4103/ajts.AJTS_151_17.
The blood specimen of a 30-year-old male donor showing a discrepancy in cell and serum grouping was targeted for detailed study at the blood bank at tertiary care hospital in South Gujarat. Forward grouping showed group as "O" RhD positive and reverse grouping as group "A." Further testing confirmed that the individual's blood group was para-Bombay A (para-AH). Family members were screened, and younger brother was also identified as para-Bombay phenotype. The para-Bombay phenotype is very rare, and only a few cases have been reported from India. This blood group is characterized by the absence of ABH antigens on red blood cells (RBC's) with the presence of ABH substances in body secretions or by the weak expression of ABH antigens on RBC's with the absence or presence of substances in body secretions. This rare phenotype can be mislabeled as "O" if all detailed investigations are not performed.
一名30岁男性献血者的血液标本在细胞和血清分组上存在差异,该标本被送往古吉拉特邦南部一家三级护理医院的血库进行详细研究。正向血型鉴定显示为“O”型RhD阳性,反向血型鉴定显示为“A”型。进一步检测证实该个体的血型为副孟买A型(副AH)。对其家庭成员进行了筛查,发现其弟弟也为副孟买血型表型。副孟买血型表型非常罕见,印度仅报道过少数病例。这种血型的特征是红细胞(RBC)上缺乏ABH抗原,但身体分泌物中存在ABH物质,或者红细胞上ABH抗原表达较弱,身体分泌物中存在或不存在这些物质。如果不进行所有详细调查,这种罕见的表型可能会被误标记为“O”型。