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医师配备的紧急医疗服务(P-EMS)对严重创伤性脑损伤患者结局的影响:文献综述。

Effect of Physician-Staffed Emergency Medical Services (P-EMS) on the Outcome of Patients with Severe Traumatic Brain Injury: A Review of the Literature.

出版信息

Prehosp Emerg Care. 2019 Sep-Oct;23(5):730-739. doi: 10.1080/10903127.2019.1575498. Epub 2019 Mar 15.

Abstract

Traumatic injury is the fourth leading cause of death in western countries and the leading cause of death in younger age. However, it is still unclear which groups of patients benefit most from advanced prehospital trauma care. A minimal amount is known about the effect of prehospital physician-based care on patients with specifically traumatic brain injury (TBI). The aim of this review is to assess the effect of physician-staffed Emergency Medical Services (EMS) on the outcome of patients with severe TBI. Literature searches have been performed in the bibliographic databases of PubMed, EMBASE and The Cochrane Library. Data concerning (physician-staffed) prehospital care for patients with severe TBI were only included if the control group was based on non-physician-staffed EMS. Primarily the mortality rate and secondarily the neurological outcome were examined. Additionally, data concerning hypotension, hypoxia, length of stay (hospital and intensive care unit) and the number of required early neurosurgical interventions were taken into account. The overall mortality was decreased in three of the fourteen included studies after the implementation of a physician in the prehospital setting. One study found also a decrease in mortality only for patients with a Glasgow Coma Scale of 6-8. Strikingly, two other studies reported higher mortality, one for all the included patients and one for patients with GCS 10-12 only. Neurological outcome was improved in five studies after prehospital deployment of a physician. One study reported that more patients had a poor neurological outcome in the P-EMS group. Results of the remaining outcome measures differed widely. The included literature did not show a clear beneficial effect of P-EMS in the prehospital management of patients with severe TBI. The available evidence showed contradictory results, suggesting more research should be performed in this field with focus on decreasing heterogeneity in the compared groups.

摘要

创伤是西方国家的第四大死亡原因,也是年轻人群死亡的主要原因。然而,目前仍不清楚哪些患者群体最受益于先进的院前创伤救治。对于基于院前医生的护理对创伤性脑损伤(TBI)患者的影响,人们知之甚少。本综述的目的是评估配备医生的紧急医疗服务(EMS)对严重 TBI 患者结局的影响。文献检索在 PubMed、EMBASE 和 The Cochrane Library 这三个文献数据库中进行。仅当对照组基于非配备医生的 EMS 时,才会纳入有关严重 TBI 患者(配备医生的)院前护理的数据。主要检查死亡率,其次是神经结局。此外,还考虑了低血压、低氧血症、住院时间(医院和重症监护病房)和需要早期神经外科干预的次数。在实施院前配备医生后,14 项纳入研究中有 3 项研究的总体死亡率降低。一项研究还发现,格拉斯哥昏迷量表评分为 6-8 的患者死亡率降低。引人注目的是,另外两项研究报告死亡率更高,一项针对所有纳入患者,另一项仅针对格拉斯哥昏迷量表评分为 10-12 的患者。在院前部署医生后,5 项研究中神经结局得到改善。一项研究报告称,在配备医生的 EMS 组中,更多患者神经结局较差。其余结局指标的结果差异很大。纳入的文献并未显示在严重 TBI 患者的院前管理中配备医生的 EMS 有明确的有益效果。现有证据显示结果存在矛盾,表明应在该领域开展更多研究,重点关注比较组的异质性降低。

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