非酒精性脂肪性肝病患者行振动控制瞬时弹性成像是否需要禁食？
Is Fasting Necessary for Individuals With Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?
机构信息
Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Department of Biostatistics, Indiana University-Purdue University, Indianapolis, Indiana, USA.
出版信息
Am J Gastroenterol. 2019 Jun;114(6):995-997. doi: 10.14309/ajg.0000000000000116.
OBJECTIVES
To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography.
METHODS
LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients.
RESULTS
A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1).
CONCLUSIONS
Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.
目的
研究经肝活检证实的非酒精性脂肪性肝病患者在进行振动控制瞬时弹性成像时进食对肝硬度测量（LSM）和受控衰减参数（CAP）的影响。
方法
在 24 例患者中，在基线时和进食后 6 小时内连续评估 LSM 和 CAP。
结果
LSM 在 2 小时时间点显著增加（26±25%，P=0.02）。CAP 评分变化很小，最大变化 3%（P＞0.1）。
结论
进行振动控制瞬时弹性成像前需要禁食 3 小时。
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