Hecher K, Ertl U, Spernol R, Haselbach H, Szalay S
Gynäkologisch-goburtshilfliche Abteilung, LKH-Klagenfurt Vorstand.
Geburtshilfe Frauenheilkd. 1988 Nov;48(11):809-13. doi: 10.1055/s-2008-1026632.
249 blood-flow measurements were carried out with pulsed Doppler-ultrasound in the umbilical arteries and the descending aorta of 188 fetuses. The PI and the RI of the recorded flowpatterns were calculated. In a retrospective study we then calculated the validity of the prediction of a pathological fetal outcome, i.e. a SGA-fetus and/or perinatal morbidity, for both indices. The sensitivity of the PI is 63%, the specificity was 98%, the sensitivity of the RI was 40%, and the specificity 98%. Therefore the sensitivity of the PI is significantly higher than that of the RI (p less than 0.05). In the second, prospective part of the study these results could be verified by means of an equivalent number of measurements to the first group (n = 249) with 178 fetuses. All the jeopardized fetuses with IUGR and perinatal morbidity (n = 13) were detected by an increased PI, but even in this group the sensitivity of the RI was only 54%. The possible reasons for these results are discussed, taking into account the different characteristics of the two indices and the influence of the heart rate on both of them.
对188例胎儿的脐动脉和降主动脉进行了249次脉冲多普勒超声血流测量。计算记录血流模式的搏动指数(PI)和阻力指数(RI)。在一项回顾性研究中,我们随后计算了这两个指数对病理性胎儿结局(即小于胎龄儿和/或围产期发病率)预测的有效性。PI的敏感性为63%,特异性为98%,RI的敏感性为40%,特异性为98%。因此,PI的敏感性显著高于RI(p<0.05)。在该研究的第二部分前瞻性研究中,通过对178例胎儿进行与第一组等量的测量(n = 249)验证了这些结果。所有患有宫内生长受限和围产期发病率的高危胎儿(n = 13)均通过PI升高检测到,但即使在该组中,RI的敏感性也仅为54%。考虑到这两个指数的不同特征以及心率对它们的影响,讨论了这些结果的可能原因。