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自体肋软骨与尸体肋软骨用于功能性鼻中隔鼻成形术后的鼻功能评估评分比较

Comparison of NOSE Scores Following Functional Septorhinoplasty Using Autologous versus Cadaveric Rib.

作者信息

Justicz Natalie, Fuller Jennifer C, Levesque Patricia, Lindsay Robin W

机构信息

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts.

Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts.

出版信息

Facial Plast Surg. 2019 Feb;35(1):103-108. doi: 10.1055/s-0039-1677718. Epub 2019 Jan 29.

Abstract

In functional septorhinoplasty (FSRP), alternative grafting material is used if septal cartilage is insufficient for reconstructive needs. Autologous costal cartilage (ACC) and irradiated homologous costal cartilage (IHCC) are compared via the Nasal Obstruction Symptom Evaluation (NOSE) scale. One-hundred forty-one patients who underwent FSRP with ACC or IHCC between January 2013 and March 2018 were administered the NOSE scale pre- and postoperatively at 2, 4, 6, and 12 months. There was no significant difference in mean NOSE scores between the ACC and IHCC cohorts at the preoperative visit (68.5 [standard deviation, SD 24.1] and 71.7 [20.1], respectively;  < 0.6) or first postoperative visit (30.4 [26.6] and 33.9 [30.4], respectively;  < 0.6) or subsequent visits. NOSE scores demonstrated a clinically and statistically significant improvement at all follow-up time points for both the ACC and IHCC groups. Patients who underwent grafting with IHCC were significantly older than those with ACC; average age of 55.6 [SD: 17.3] versus 40.1 [SD:12.1]; ( < 0.001). Two IHCC (0.05%) patients had postoperative infections; both resolved with antibiotics, but one required revision surgery. Both ACC and IHCC provide reliable grafting material when septal cartilage is insufficient. In FSRP for nasal airway obstruction, ACC and IHCC both provide a clinically and statistically significant reduction in NOSE scores postoperatively that remain stable between follow-up time points. The authors find no difference in NOSE scores between the ACC and IHCC groups; however, IHCC did have a higher rate of postoperative infection. Both materials should be discussed with patients and are an important part of the informed consent process.

摘要

在功能性鼻中隔成形术(FSRP)中,如果鼻中隔软骨不足以满足重建需求,则使用替代移植材料。通过鼻阻塞症状评估(NOSE)量表对自体肋软骨(ACC)和辐照同种异体肋软骨(IHCC)进行比较。对2013年1月至2018年3月期间接受ACC或IHCC FSRP的141例患者在术前以及术后2、4、6和12个月进行NOSE量表评估。ACC组和IHCC组在术前访视时(分别为68.5[标准差,SD 24.1]和71.7[20.1];P<0.6)、首次术后访视时(分别为30.4[26.6]和33.9[30.4];P<0.6)或随后的访视中,平均NOSE评分无显著差异。ACC组和IHCC组在所有随访时间点的NOSE评分均显示出临床和统计学上的显著改善。接受IHCC移植的患者明显比接受ACC移植的患者年龄大;平均年龄分别为55.6[SD:17.3]和40.1[SD:12.1];(P<0.001)。2例(0.05%)接受IHCC移植的患者术后发生感染;两者均通过抗生素治愈,但其中1例需要进行翻修手术。当鼻中隔软骨不足时,ACC和IHCC均可提供可靠的移植材料。在治疗鼻气道阻塞的FSRP中,ACC和IHCC术后均能在临床和统计学上显著降低NOSE评分,且随访时间点之间保持稳定。作者发现ACC组和IHCC组之间的NOSE评分无差异;然而,IHCC的术后感染率较高。两种材料都应与患者讨论,并且是知情同意过程的重要组成部分。

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