阿米巴肝脓肿：儿童经皮穿刺抽吸与置管引流的治疗效果

Amoebic liver abscess: Outcomes of percutaneous needle aspiration vs drain placement in paediatric population.

作者信息

Salim Areej, Jeelani Sarah Masroor, Qazi Saqib Hamid, Mirza Waseem

机构信息

Paediatric Surgery, Department of surgery, Aga Khan University, Karachi, Pakistan.

Paediatric Surgery, Department of surgery Aga Khan University, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2019 Feb;69(Suppl 1)(1):S29-S32.

PMID:30697015

Abstract

OBJECTIVE

To compare the effectiveness of percutaneous catheter drain placement with percutaneous needle aspiration in terms of hospital stay, time to resolution of symptoms and cost of intervention performed.

METHODS

The retrospective cohort study was conducted at Aga Khan University Hospital, Karachi, and comprised data of patients with amoebic liver abscess from, January 2006 to December 2016 which was collected using non-probability purposeful sampling. Primary outcome included length of hospital stay, time to resolution of symptoms and cost of intervention. Secondary outcomes included development of complications, need for re-intervention and abscess resolution. SPSS 22 was used for data analysis. .

RESULTS

Of the 62 patients, 36(58%) underwent percutaneous needle aspiration Group A, and 26(42%) were treated with percutaneous catheter drain placement Group B. Both groups were malnourished and anaemic at presentation. Overall, 56(90.3%) patients had single abscess and 44(71%) had it in the right lobe. Mean duration of symptoms was less in Group B compared to Group A (11.2±4.5 versus 16.4±3.2 days). Mean abscess size was 6.13cm ± 9.75cm in Group A and 7.40cm ± 8.40cm in Group B. The mean length of hospital stay Group A was shorter than in Group B (p=0.047) with earlier resolution of symptoms (p=0.027).

CONCLUSION

Both methods were found to be effective in treating amoebic liver abscess in children, but percutaneous needle aspiration was more effective.

摘要

目的

比较经皮导管引流与经皮穿刺抽吸在住院时间、症状缓解时间及干预成本方面的有效性。

方法

本回顾性队列研究在卡拉奇的阿迦汗大学医院进行，纳入了2006年1月至2016年12月期间阿米巴肝脓肿患者的数据，采用非概率目的抽样法收集。主要结局包括住院时间、症状缓解时间及干预成本。次要结局包括并发症的发生、再次干预的需求及脓肿消退情况。使用SPSS 22进行数据分析。

结果

62例患者中，36例（58%）接受经皮穿刺抽吸（A组），26例（42%）接受经皮导管引流（B组）。两组患者就诊时均存在营养不良和贫血。总体而言，56例（90.3%）患者为单个脓肿，44例（71%）位于右叶。B组症状的平均持续时间短于A组（11.2±4.5天对16.4±3.2天）。A组脓肿平均大小为6.13cm±9.75cm，B组为7.40cm±8.40cm。A组的平均住院时间短于B组（p = 0.047），症状缓解更早（p = 0.027）。