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胸痛可能是匹伐他汀(力清之)的副作用。

Chest pain as a possible side effect of pitavastatin (Livalo).

作者信息

AlZahrani Nada R, Yassin Amna F

机构信息

Department of Internal Medicine, King Fahad Medical Military Complex, Saudi Arabia.

出版信息

J Family Community Med. 2019 Jan-Apr;26(1):61-63. doi: 10.4103/jfcm.JFCM_74_18.

Abstract

Coronary heart disease is a serious complication of dyslipidemia. Pitavastatin is a more commonly prescribed medication for the treatment of dyslipidemia. Here, we report the case of a 37-year-old female, a known patient with well-controlled bronchial asthma. She was recently found to be dyslipidemic and started on pitavastatin calcium 4 mg once a day (OD). On the 10 day of treatment, she began to have crushing chest pain and was admitted to the hospital. All investigations for coronary heart disease came out negative. Her symptoms improved dramatically when pitavastatin was stopped. Pitavastatin is reported to cause myalgia and muscle spasm, especially at higher doses. There is evidence in literature that this medication might cause chest pain in old obese ladies if taken at high doses. We report this case as a possibility of chest pain even in younger females.

摘要

冠心病是血脂异常的一种严重并发症。匹伐他汀是治疗血脂异常时更常用的处方药。在此,我们报告一例37岁女性病例,该患者为已知的支气管哮喘控制良好的患者。她最近被发现血脂异常,并开始每日一次服用4毫克匹伐他汀钙。在治疗的第10天,她开始出现压榨性胸痛并入院。所有冠心病相关检查结果均为阴性。停用匹伐他汀后,她的症状显著改善。据报道,匹伐他汀会引起肌痛和肌肉痉挛,尤其是在高剂量时。文献中有证据表明,这种药物如果高剂量服用,可能会导致老年肥胖女性胸痛。我们报告此病例,提示即使是年轻女性也可能出现胸痛。

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