Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv University, Israel.
Int Wound J. 2019 Jun;16(3):684-695. doi: 10.1111/iwj.13082. Epub 2019 Jan 29.
Patients who are immobile endure prolonged bodyweight-related compressive, tensional and shear loads at their body-support contact areas that over time may lead to the onset of pressure ulcers (PUs). Approximately, one-third of the common sacral PUs are severe and classified as category 3 or 4. If a PU has occurred, off-loading is the basic, commonly accepted clinical intervention; however, in many situations, complete off-loading of sacral PUs is not possible. Minimising the exposure of wounds and their surroundings to elevated mechanical loads is crucial for healing. Accordingly, in the present study, we aimed to investigate the biomechanical effects of the structural and mechanical properties of different treatment dressings on stresses in soft tissues surrounding a non-offloaded sacral PU in a supine patient. Using a novel three-dimensional anatomically realistic finite element modelling framework, we have compared performances of three dressing designs: (a) The Mepilex Border Sacrum (MBS) multilayer anisotropic silicone foam dressing (Mölnlycke Health Care), (b) an isotropic stiff dressing, and (c) an isotropic flexible dressing. Using our newly developed protective efficacy index (PEI) and aggravation index (AI) for assessing prophylactic and treatment dressings, we identified the anisotropic stiffness feature of the MBS dressing as a key design element.
对于不能活动的患者,其身体支撑接触区域会持续承受长时间的与体重相关的压缩、拉伸和剪切负荷,随着时间的推移,可能会导致压疮(PU)的发生。大约三分之一的常见骶部 PU 较为严重,被归类为 3 类或 4 类。如果已经发生了 PU,减压是基本的、公认的临床干预措施;然而,在许多情况下,骶部 PU 无法完全减压。使伤口及其周围组织免受高机械负荷的暴露对于愈合至关重要。因此,在本研究中,我们旨在研究不同治疗敷料的结构和力学性能对仰卧位未减压骶部 PU 周围软组织应力的生物力学影响。使用新颖的三维解剖学逼真有限元建模框架,我们比较了三种敷料设计的性能:(a)Mepilex Border Sacrum(MBS)多层各向异性硅酮泡沫敷料(Mölnlycke Health Care),(b)各向同性刚性敷料,和(c)各向同性柔性敷料。使用我们新开发的防护效果指数(PEI)和加重指数(AI)来评估预防性和治疗性敷料,我们确定了 MBS 敷料的各向异性刚度特征是一个关键设计要素。