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儿科门诊手术后感染:发生率和危险因素。

Infections after pediatric ambulatory surgery: Incidence and risk factors.

机构信息

1Division of Infectious Diseases and Center for Pediatric Clinical Effectiveness,Children's Hospital of Philadelphia,Philadelphia,Pennsylvania.

3Department of Biostatistics and Epidemiology,Perelman School of Medicine,University of Pennsylvania,Philadelphia,Pennsylvania.

出版信息

Infect Control Hosp Epidemiol. 2019 Feb;40(2):150-157. doi: 10.1017/ice.2018.211.

Abstract

OBJECTIVE

To describe the epidemiology of surgical site infections (SSIs) after pediatric ambulatory surgery.

DESIGN

Observational cohort study with 60 days follow-up after surgery.

SETTING

The study took place in 3 ambulatory surgical facilities (ASFs) and 1 hospital-based facility in a single pediatric healthcare network.ParticipantsChildren <18 years undergoing ambulatory surgery were included in the study. Of 19,777 eligible surgical encounters, 8,502 patients were enrolled.

METHODS

Data were collected through parental interviews and from chart reviews. We assessed 2 outcomes: (1) National Healthcare Safety Network (NHSN)-defined SSI and (2) evidence of possible infection using a definition developed for this study.

RESULTS

We identified 21 NSHN SSIs for a rate of 2.5 SSIs per 1,000 surgical encounters: 2.9 per 1,000 at the hospital-based facility and 1.6 per 1,000 at the ASFs. After restricting the search to procedures completed at both facilities and adjustment for patient demographics, there was no difference in the risk of NHSN SSI between the 2 types of facilities (odds ratio, 0.7; 95% confidence interval, 0.2-2.3). Within 60 days after surgery, 404 surgical patients had some or strong evidence of possible infection obtained from parental interview and/or chart review (rate, 48 SSIs per 1,000 surgical encounters). Of 306 cases identified through parental interviews, 176 cases (57%) did not have chart documentation. In our multivariable analysis, older age and black race were associated with a reduced risk of possible infection.

CONCLUSIONS

The rate of NHSN-defined SSI after pediatric ambulatory surgery was low, although a substantial additional burden of infectious morbidity related to surgery might not have been captured by standard surveillance strategies and definitions.

摘要

目的

描述小儿门诊手术术后手术部位感染(SSI)的流行病学情况。

设计

术后 60 天随访的观察性队列研究。

地点

该研究在单一儿童保健网络中的 3 个门诊外科设施(ASFs)和 1 个医院内设施进行。

参与者

纳入接受门诊手术的 <18 岁儿童。在 19777 例符合条件的手术中,有 8502 例患者入组。

方法

通过父母访谈和病历回顾收集数据。我们评估了 2 个结果:(1)国家医疗保健安全网络(NHSN)定义的 SSI 和(2)使用为本研究制定的定义确定的感染证据。

结果

我们确定了 21 例 NHSN SSI,发生率为每 1000 例手术发生 2.5 例 SSI:医院内设施为每 1000 例 2.9 例,ASFs 为每 1000 例 1.6 例。在限制搜索范围至在这两个设施都完成的手术,并对患者人口统计学进行调整后,两种类型的设施之间 NHSN SSI 的风险无差异(比值比,0.7;95%置信区间,0.2-2.3)。在手术后 60 天内,通过父母访谈和/或病历回顾获得了 404 名手术患者的某种或强烈的感染可能的证据(发生率,每 1000 例手术发生 48 例 SSI)。在通过父母访谈确定的 306 例病例中,有 176 例(57%)没有病历记录。在多变量分析中,年龄较大和黑种人种族与感染可能性降低相关。

结论

小儿门诊手术后 NHSN 定义的 SSI 发生率较低,但可能未通过标准监测策略和定义捕捉到与手术相关的大量额外传染性发病率。

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