Bertrand Romero Henrique Carvalho, Bertrand Adriana Leite Xavier, Gomes Thais Mota, Ferreira Adalgisa de Sousa Paiva
Departamento de Medicina II, Universidade Federal do Maranhão, São Luís, MA, Brazil.
Departamento de Oftalmologia, Centro de Ensino Unificado do Maranhão, São Luís, MA, Brazil.
Arq Bras Oftalmol. 2019 Mar-Apr;82(2):161-167. doi: 10.5935/0004-2749.20190027. Epub 2019 Jan 24.
This review aims to caution ophthalmologists about the ocular consequences leading to the diagnosis of hepatitis C virus infection. In addition, in this context, the effects of old and new drugs are discussed in the ophthalmological setting. The importance of early diagnosis and the curative treatment of the disease has been reported in the national and international literature, demonstrating that its progression has important implications for daily clinical and surgical ophthalmological practice. Despite the scarcity of studies on new direct-acting antiviral drugs, fewer side effects of these drugs have been shown when compared with conventional interferon treatment with or without ribavirin. The ophthalmologist's risk of becoming infected, as demonstrated by the presence of the virus in ocular structures, and the possibility of contamination, is also discussed.
本综述旨在提醒眼科医生注意导致丙型肝炎病毒感染诊断的眼部后果。此外,在此背景下,还讨论了新旧药物在眼科环境中的作用。国家和国际文献报道了该疾病早期诊断和治愈性治疗的重要性,表明其进展对日常临床和眼科手术实践具有重要意义。尽管关于新型直接作用抗病毒药物的研究较少,但与使用或不使用利巴韦林的传统干扰素治疗相比,这些药物的副作用更少。文中还讨论了眼科医生因眼部结构中存在病毒而被感染的风险以及污染的可能性。