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关注丙型肝炎:一篇综述

An eye on hepatitis C: a review.

作者信息

Bertrand Romero Henrique Carvalho, Bertrand Adriana Leite Xavier, Gomes Thais Mota, Ferreira Adalgisa de Sousa Paiva

机构信息

Departamento de Medicina II, Universidade Federal do Maranhão, São Luís, MA, Brazil.

Departamento de Oftalmologia, Centro de Ensino Unificado do Maranhão, São Luís, MA, Brazil.

出版信息

Arq Bras Oftalmol. 2019 Mar-Apr;82(2):161-167. doi: 10.5935/0004-2749.20190027. Epub 2019 Jan 24.

DOI:10.5935/0004-2749.20190027
PMID:30698233
Abstract

This review aims to caution ophthalmologists about the ocular consequences leading to the diagnosis of hepatitis C virus infection. In addition, in this context, the effects of old and new drugs are discussed in the ophthalmological setting. The importance of early diagnosis and the curative treatment of the disease has been reported in the national and international literature, demonstrating that its progression has important implications for daily clinical and surgical ophthalmological practice. Despite the scarcity of studies on new direct-acting antiviral drugs, fewer side effects of these drugs have been shown when compared with conventional interferon treatment with or without ribavirin. The ophthalmologist's risk of becoming infected, as demonstrated by the presence of the virus in ocular structures, and the possibility of contamination, is also discussed.

摘要

本综述旨在提醒眼科医生注意导致丙型肝炎病毒感染诊断的眼部后果。此外,在此背景下,还讨论了新旧药物在眼科环境中的作用。国家和国际文献报道了该疾病早期诊断和治愈性治疗的重要性,表明其进展对日常临床和眼科手术实践具有重要意义。尽管关于新型直接作用抗病毒药物的研究较少,但与使用或不使用利巴韦林的传统干扰素治疗相比,这些药物的副作用更少。文中还讨论了眼科医生因眼部结构中存在病毒而被感染的风险以及污染的可能性。

相似文献

1
An eye on hepatitis C: a review.关注丙型肝炎:一篇综述
Arq Bras Oftalmol. 2019 Mar-Apr;82(2):161-167. doi: 10.5935/0004-2749.20190027. Epub 2019 Jan 24.
2
[Diagnosis, treatment, and follow-up of hepatitis C-virus related liver disease. Hungarian national consensus guideline].[丙型肝炎病毒相关肝病的诊断、治疗及随访。匈牙利国家共识指南]
Orv Hetil. 2014 Mar;155 Suppl:3-24. doi: 10.1556/OH.2013.29893.
3
Side effects. Safety and effectiveness of interferon and ribavirin in HIV+ people co-infected with hepatitis C virus.副作用。干扰素和利巴韦林在合并感染丙型肝炎病毒的HIV阳性人群中的安全性和有效性。
TreatmentUpdate. 2001 Winter;12(8):4-5.
4
Managing hepatitis C infection in HIV-positive patients.对艾滋病毒呈阳性患者的丙型肝炎感染进行管理。
AIDS Clin Care. 2000 Sep;12(9):71-5, 78.
5
Scleritis and peripheral ulcerative keratitis with hepatitis C virus-related cryoglobulinemia.巩膜炎和周边溃疡性角膜炎伴丙型肝炎病毒相关冷球蛋白血症。
Arch Ophthalmol. 2007 Jun;125(6):852-3. doi: 10.1001/archopht.125.6.852.
6
Infection fighters. Hepatitis C--is a cure possible?抗感染卫士。丙型肝炎——有望治愈吗?
TreatmentUpdate. 2005 Jan-Feb;17(1):8-9.
7
Sustained viral response to interferon and ribavirin in liver transplant recipients with recurrent hepatitis C.肝移植受者复发性丙型肝炎对干扰素和利巴韦林的持续病毒学应答
Liver Transpl. 2004 Feb;10(2):199-207. doi: 10.1002/lt.20074.
8
[Comparison of hepatitis C viral RNA and core antigen kinetics in the therapeutic follow up of hepatitis C virus and human immunodeficiency virus co-infected patients, treated by bitherapy interferon-ribavirin, within the framework of RIBAVIC protocol].[在RIBAVIC方案框架内,对接受干扰素-利巴韦林联合治疗的丙型肝炎病毒和人类免疫缺陷病毒合并感染患者进行治疗随访时,丙型肝炎病毒RNA与核心抗原动力学的比较]
Pathol Biol (Paris). 2004 Nov;52(9):522-8. doi: 10.1016/j.patbio.2004.07.036.
9
Ophthalmological complications in hepatitis C virus infection: side effect of interferon therapy or a direct role of HCV?丙型肝炎病毒感染的眼科并发症:干扰素治疗的副作用还是 HCV 的直接作用?
Biomed Pharmacother. 2011 Jul;65(4):317-8. doi: 10.1016/j.biopha.2011.04.004. Epub 2011 May 30.
10
[Antiviral therapy of hepatitis C].[丙型肝炎的抗病毒治疗]
Z Gastroenterol. 2000 Mar;38(3):259-69. doi: 10.1055/s-2000-14867.

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Int Ophthalmol. 2024 Apr 15;44(1):177. doi: 10.1007/s10792-024-03103-y.
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