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[严重上颌前牙区牙槽嵴萎缩的重建:多种手术技术的联合应用]

[Reconstraction of severe anterior maxillary ridge atrophy: combination of several surgical techniques].

作者信息

Schwartz-Arad D

出版信息

Refuat Hapeh Vehashinayim (1993). 2017 Jan;34(1):45-51, 74.

Abstract

Achieving an esthetic and functional implant supported restoration in the maxillary anterior segment can be challenging especially in a severe atrophy. The reconstruction of atrophic alveolar ridges using autologous Onlay Bone Grafting (AOBG) was originally reported in 1975. It's still considered as the 'gold standard' bone-grafting material, as if combines all properties required in a bone graft material; osteogenesis, osteoinduction, and osteoconduction. The use of intraoral donor sites, such as the mandibular symphysis, and ramus, offers no cutaneous scarring, minimal discomfort, and less morbidity compared with the extraoral sources. In addition, intraoral sites comprises good bone quality, convenient surgical access, good incorporation with a short healing time, high biocompatibility and embryological proximity. Furthermore, recent studies describe extensive bone deficiency reconstruction using solely intraoral block bone grafts by means of the multities technique, possibly by re-harvesting bone from the same donor site. the anatomic configuration in the atrophic site, influences the surgical choices, i.e. when surgical reconstruction is performed in the anterior atrophic maxilla, the reference standard of care would be to perform subnasal augmentation procedure for vertical augmentation with additional vertical and/or horizontal AOBG augmentation if necessary. For the AOBG to be accepted in the augmented area, other elements are introduced for support and rehabilitation; Growth Factor (GFs) for example, are expressed during different phases of tissue healing and are therefore a key element in promoting tissue regeneration. Platelet Rich Plasma (PRP) is an inexpensive way to obtain many GFs in physiological proportion and therefore has gained wide interest as a therapy for both soft and hard tissue injuries. In addition, Platelet-Poor Plasma (PPP) is composed of acellular plasma containing fibrinogen and growth factors, and is used as a "biological membrane" to cover the entire augmented area and donor sites that were filled with bone substitutes saturated in PRP or BMAC (Bone Marrow Aspirate Concentrate)as scaffold. Mesenchymal stem cells (originated from the BMAC) can be differentiated into diverse tissues, including bones. It has been suggested that transplantation of autologous stem cells from bone marrow can as well enhance bone healing. Patient satisfaction is a key factor in the success of implant therapy, especially in the anterior maxilla. Defect in the gingival continuity of shape cannot be always compensated by the quality of the dental restoration only. The challenge is that hard and soft tissue augmentation is necessary to achieve a successful result. The challenge is that hard and soft tissue augmentation is necessary to achieve a successful result. The aesthetics of the patient can be improved using sub-epithelial connective tissue graft. The effectiveness of the combined surgical treatment described, is the fact that AOBG, was used fort he severe atrophic anterior maxilla reconstruction. Augmentation of atrophied maxilla through the positioning of horizontal and vertical AOBG, should be considered reliable, safe, and very effective in obtaining apico-coronal and bucco-lingual dimensions improving implant trajectory for high bone graft success rate following a high long-term implant survival rate.

摘要

在上颌前牙区实现美观且功能良好的种植体支持修复具有挑战性,尤其是在严重萎缩的情况下。1975年首次报道了使用自体块状骨移植(AOBG)重建萎缩性牙槽嵴。它仍被视为“金标准”骨移植材料,因为它具备骨移植材料所需的所有特性;成骨、骨诱导和骨传导。与口外供区相比,使用口内供区,如下颌联合和下颌升支,不会留下皮肤瘢痕,不适感最小,发病率也较低。此外,口内供区骨质良好,手术入路方便,愈合时间短,融合良好,生物相容性高且胚胎学关系相近。此外,最近的研究描述了通过多部位技术仅使用口内块状骨移植进行广泛骨缺损重建,可能是通过从同一供区再次获取骨组织。萎缩部位的解剖结构会影响手术选择,即当在上颌前牙区萎缩部位进行手术重建时,标准的治疗方法是进行鼻下增高术以进行垂直增高,必要时可额外进行垂直和/或水平AOBG增高。为了使AOBG在增高区域被接受,还引入了其他元素用于支持和修复;例如,生长因子(GFs)在组织愈合的不同阶段表达,因此是促进组织再生的关键因素。富血小板血浆(PRP)是一种以生理比例获取多种GFs的廉价方法,因此作为一种治疗软硬组织损伤的方法受到了广泛关注。此外,贫血小板血浆(PPP)由含有纤维蛋白原和生长因子的无细胞血浆组成,用作“生物膜”覆盖整个增高区域以及填充有饱和PRP或骨髓抽吸浓缩物(BMAC)作为支架的骨替代物的供区。间充质干细胞(源自BMAC)可以分化为多种组织,包括骨组织。有人提出,移植来自骨髓的自体干细胞也可以促进骨愈合。患者满意度是种植治疗成功的关键因素,尤其是在上颌前牙区。牙龈形态连续性的缺陷不能总是仅通过牙齿修复的质量来弥补。挑战在于,为了获得成功的结果,软硬组织增高是必要的。挑战在于,为了获得成功的结果,软硬组织增高是必要的。使用上皮下结缔组织移植可以改善患者的美观。所描述的联合手术治疗的有效性在于,AOBG被用于严重萎缩的上颌前牙区重建。通过水平和垂直AOBG定位对上颌萎缩进行增高,在获得根尖 - 冠向和颊舌向尺寸、改善种植体植入轨迹以实现高骨移植成功率和高长期种植体存活率方面应被认为是可靠、安全且非常有效的。

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