Division of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, California, USA.
Institute for Health Policy Studies, School of Medicine, University of California, San Francisco, California, USA.
BMJ Open. 2019 Jan 29;9(1):e026298. doi: 10.1136/bmjopen-2018-026298.
From 2011 to 2013, the Global Fund (GF) supported needle and syringe programmes in Mexico to prevent transmission of HIV among people who inject drugs. It remains unclear how GF withdrawal affected the costs, quality and coverage of needle and syringe programme provision.
Costing study and longitudinal cohort study.
Tijuana, Mexico.
Personnel from a local needle and syringe programme (n=6) and people who inject drugs (n=734) participating in a longitudinal study.
Provision of needle and syringe programme services and cost (per contact and per syringe distributed, in 2017 $USD) during GF support (2012) and after withdrawal (2015/16). An additional outcome included needle and syringe programme utilisation from a concurrent cohort of people who inject drugs during and after GF withdrawal.
During the GF period, the needle and syringe programme distributed 55 920 syringes to 932 contacts (60 syringes/contact) across 14 geographical locations. After GF withdrew, the needle and syringe programme distributed 10 700 syringes to 2140 contacts (five syringes/contact) across three geographical locations. During the GF period, the cost per harm reduction contact was approximately 10-fold higher compared with after GF ($44.72 vs $3.81); however, the cost per syringe distributed was nearly equal ($0.75 vs $0.76) due to differences in syringes per contact and reductions in ancillary kit components. The mean log odds of accessing a needle and syringe programme in the post-GF period was significantly lower than during the GF period (p=0.02).
Withdrawal of GF support for needle and syringe programme provision in Mexico was associated with a substantial drop in provision of sterile syringes, geographical coverage and recent clean syringe utilisation among people who inject drugs. Better planning is required to ensure harm reduction programme sustainability is at scale after donor withdrawal.
从 2011 年到 2013 年,全球基金(GF)支持墨西哥的针具交换项目,以预防注射吸毒者之间 HIV 的传播。目前尚不清楚 GF 撤资对针具交换项目提供的成本、质量和覆盖范围有何影响。
成本研究和纵向队列研究。
墨西哥蒂华纳。
当地针具交换项目的工作人员(n=6)和参与纵向研究的注射吸毒者(n=734)。
在 GF 支持期间(2012 年)和撤出后(2015/16 年)提供针具交换项目服务和成本(按每次接触和每次分发的注射器计算,以 2017 年美元计算)。另一个结果包括在 GF 撤出期间和之后,同时接受注射吸毒者的针具交换项目的利用情况。
在 GF 期间,针具交换项目在 14 个地理位置向 932 名接触者分发了 55920 支注射器(每名接触者 60 支注射器)。在 GF 撤出后,针具交换项目在三个地理位置向 2140 名接触者分发了 10700 支注射器(每名接触者 5 支注射器)。在 GF 期间,每减少一次伤害的接触成本是 GF 之后的约 10 倍(44.72 美元与 3.81 美元);然而,由于每次接触注射器数量的差异和辅助工具包组件的减少,每次分发注射器的成本几乎相等(0.75 美元与 0.76 美元)。在 GF 之后,获得针具交换项目的平均对数可能性显著低于 GF 期间(p=0.02)。
墨西哥针具交换项目提供的 GF 支持撤出与无菌注射器的提供、地理覆盖范围和注射吸毒者最近清洁注射器的使用显著下降有关。在捐助者撤出后,需要更好的规划以确保减少伤害方案的可持续性达到规模。