Choudhary Gagandeep, Manapragada Padma P, Wallace Eric, Bhambhvani Pradeep
Division of Molecular Imaging and Therapeutics, Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama; and
Division of Molecular Imaging and Therapeutics, Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama; and.
J Nucl Med Technol. 2019 Jun;47(2):163-168. doi: 10.2967/jnmt.118.223156. Epub 2019 Jan 29.
Dialysis is an artificial process to remove waste products and excess water from the body in patients with kidney failure. Two main types of dialysis are available. Hemodialysis, which uses an artificial filtration apparatus, is usually done at specialized centers but can be done in a patient's home. Peritoneal dialysis functions by placing dialysis fluid, also called dialysate, into the peritoneal cavity, allowing for solute to be removed from the peritoneal capillaries through diffusion across a chemical gradient into the dialysate and removal of water through an osmotic gradient created by hypertonic dextrose. Peritoneal dialysis can be either automated, which is done with the help of a machine called a cycler, or continuous ambulatory, which is a process involving multiple exchanges a day and is performed using only gravity to infuse and drain the solution from the peritoneal cavity. For many reasons, the number of people using home dialysis has recently started to rise, with the largest increase in the United States occurring after the implementation of the prospective bundled payment system for end-stage renal disease. With the increased use of home dialysis, potential complications will increase as well. It is imperative that our health-care system be poised not only to increase the number of home dialysis patients but also to diagnose and manage any complications. Nuclear imaging is a commonly available modality to detect various complications related to peritoneal dialysis. In this review article, we discuss the role of peritoneal scintigraphy in detecting some noninfectious peritoneal dialysis complications, with emphasis on scintigraphy technique; imaging time points; the role of planar, SPECT, and SPECT/CT imaging; and the clinical indications, with illustrative case examples.
透析是一种人工过程,用于清除肾衰竭患者体内的废物和多余水分。主要有两种透析方式。血液透析使用人工过滤装置,通常在专门的中心进行,但也可以在患者家中进行。腹膜透析的原理是将透析液(也称为腹透液)注入腹腔,使溶质通过化学梯度扩散从腹膜毛细血管进入透析液,同时通过高渗葡萄糖产生的渗透梯度排出水分。腹膜透析可以是自动化的,借助一种称为循环器的机器完成;也可以是持续非卧床式的,这是一个每天进行多次交换的过程,仅利用重力将溶液注入和排出腹腔。由于多种原因,最近在家中进行透析的人数开始增加,其中美国增幅最大,这是在实施终末期肾病前瞻性捆绑支付系统之后。随着家庭透析使用的增加,潜在并发症也会增多。我们的医疗保健系统不仅必须准备好增加家庭透析患者的数量,而且要诊断和处理任何并发症。核医学成像是检测与腹膜透析相关各种并发症的常用方法。在这篇综述文章中,我们讨论腹膜闪烁显像在检测一些非感染性腹膜透析并发症中的作用,重点是闪烁显像技术、成像时间点、平面显像、单光子发射计算机断层扫描(SPECT)和SPECT/CT成像的作用以及临床适应证,并配有实例说明。