Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Department of Ultrasound, Changsha Hospital for Maternal & Child Health Care, Changsha, China.
Sci Rep. 2019 Jan 30;9(1):943. doi: 10.1038/s41598-018-37268-1.
To provide useful information for diagnosing and predicting fetal intraabdominal extralobar pulmonary sequestration (IEPS), a retrospective review of diagnostic approaches was conducted. Ultrasonography was performed serially in 21 fetuses with IEPS from 2005 to 2017. Prenatal sonographic features, treatment, and outcomes of each case were evaluated and collected. These cases of IEPS were also compared to 43 cases previously reported by other researchers from 1986 to 2017. Of the 21 sonographic features, 14 (67%) were hyperechoic, 21 (100%) were well circumscribed, and 17 (81%) depicted a mass that shifted with fetal breaths/hiccups non-synchronized with adjacent organs (sliding sign). Feeding arteries were detected prenatally in 18 patients (86%). The lesion volume was 10.17 ± 4.66 cm, the congenital cystic adenomatoid malformation volume ratio and cardiothoracic ratio were in normal range. The gestational age at diagnosis, location and echotexture of the lesion, and rate of surgical treatment were similar to previous studies, but with a significantly higher rate of detected feeding arteries (P < 0.01), and associated anomalies (P < 0.01). All infants who underwent surgery after birth had satisfactory outcomes. The sliding sign and feeding artery are essential features of IEPS in prenatal diagnosis.
为了提供有助于诊断和预测胎儿腹内叶外型肺隔离症（IEPS）的信息，我们对诊断方法进行了回顾性分析。对 2005 年至 2017 年间 21 例 IEPS 胎儿进行了连续超声检查。评估并收集了每个病例的产前超声特征、治疗和结局。将这些 IEPS 病例与 1986 年至 2017 年期间其他研究人员报告的 43 例进行了比较。在 21 个超声特征中，14 个（67%）呈高回声，21 个（100%）边界清楚，17 个（81%）描绘了一个随胎儿呼吸/打嗝而移动的肿块，与邻近器官不同步（滑动征）。18 例患者（86%）在产前检测到供血动脉。病变体积为 10.17±4.66cm3，先天性囊性腺瘤样畸形体积比和心胸比均在正常范围内。诊断时的胎龄、病变的位置和回声特征以及手术治疗率与以往研究相似，但检测到的供血动脉（P<0.01）和相关畸形（P<0.01）的发生率明显更高。所有出生后接受手术的婴儿均获得满意的结局。滑动征和供血动脉是产前诊断 IEPS 的重要特征。
