原发性甲状旁腺功能亢进症在内分泌科住院患者临床中的特征。

Primary hyperparathyroidism clinical features on endocrinology in-patients clinic.

作者信息

Sapozhnikova I E

机构信息

Kirov State Medical University, the Ministry of Health of the Russia, Kirov, Russia.

出版信息

Ter Arkh. 2018 Nov 22;90(10):51-54. doi: 10.26442/terarkh2018901051-54.

DOI:10.26442/terarkh2018901051-54

PMID:30701796

Abstract

AIM

The analysis clinical features of primary hyperparathyroidism on endocrinology in-patients clinic.

MATERIALS AND METHODS

Open retrospective study, included data of patients who were hospitalized at Kirov Regional Hospital with primary hyperparathyroidism from January 01, 2013 to December 31, 2016.

RESULTS

23 patients were hospitalized. Their age is 24-78 years old (mediana 59 [52; 65] years old). There are 20 (87%) women, and 3 (13%) men. Manifest forms of primary hyperparathyroidism were detected in 18 (78.3%) patients, mild forms - in 5 (21.7%) patients. Pathological fracture had 7 (30.4%) patients including 3 (13%) vertebrae and hip fracture, urolithiasis had 10 (43.5%) persons. High blood calcium or parathyroma in ultra-sound were initially revealed in 8 (34.8%) patients 4 (50%) of them had manifest primary hyperparathyroidism. Period before diagnosis was 2 years and more in 10 (43.5%) patients.

CONCLUSION

Clinical features of primary hyperparathyroidism are prevalence of manifest forms, late diagnosis, and high enough frequent of accidental reveal (including persons with representative symptoms).

摘要

目的

分析内分泌科住院患者原发性甲状旁腺功能亢进症的临床特征。

材料与方法

开放性回顾性研究，纳入2013年1月1日至2016年12月31日期间在基洛夫地区医院因原发性甲状旁腺功能亢进症住院的患者数据。

结果

共23例患者住院。年龄24 - 78岁（中位数59[52；65]岁）。女性20例（87%），男性3例（13%）。18例（78.3%）患者检测到原发性甲状旁腺功能亢进症的明显形式，5例（21.7%）患者为轻度形式。7例（30.4%）患者发生病理性骨折，其中3例（13%）为椎骨和髋部骨折；10例（43.5%）患者有尿路结石。8例（34.8%）患者最初发现血钙升高或超声检查发现甲状旁腺瘤，其中4例（50%）有明显的原发性甲状旁腺功能亢进症。10例（43.5%）患者诊断前时间为2年或更长。