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感染性全膝关节置换术后基于价值的结局模型中需要风险调整。

Risk Adjustment Is Necessary in Value-based Outcomes Models for Infected TKA.

机构信息

P. M. Courtney, Rothman Institute, Department of Orthopaedic Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA A. J. Boniello, Department of Orthopaedic Surgery, Drexel University College of Medicine, Philadelphia, PA, USA C. J. Della Valle, Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA G.-C. Lee, Department of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Penn Presbyterian Medical Center, Philadelphia, PA, USA.

出版信息

Clin Orthop Relat Res. 2018 Oct;476(10):1940-1948. doi: 10.1007/s11999.0000000000000134.

Abstract

BACKGROUND

The Medicare Access and CHIP Reauthorization Act of 2015 provides the framework to link reimbursement for providers based on outcome metrics. Concerns exist that the lack of risk adjustment for patients undergoing revision TKA for an infection may cause problems with access to care.

QUESTIONS/PURPOSES: (1) After controlling for confounding variables, do patients undergoing revision TKA for infection have higher 30-day readmission, reoperation, and mortality rates than those undergoing revision TKA for aseptic causes? (2) Compared with patients undergoing revision TKA who are believed not to have infections, are patients undergoing revision for infected TKAs at increased risk for complications?

METHODS

We queried the American College of Surgeons National Surgical Quality Improvement Program database for patients undergoing revision TKA from 2012 to 2015 identified by Current Procedural Terminology (CPT) codes 27486, 27487, and 27488. Of the 10,848 patients identified, four were excluded with a diagnosis of malignancy (International Classification of Diseases, 9th Revision code 170.7, 170.9, 171.8, or 198.5). This validated, national database records short-term outcome data for inpatient procedures and does not rely on administrative coding data. Demographic variables, comorbidities, and outcomes were compared between patients believed to have infected TKAs and those undergoing revision for aseptic causes. A multivariate logistic regression analysis was performed to identify independent factors associated with complications, readmissions, reoperations, and mortality.

RESULTS

After controlling for demographic factors and medical comorbidities, TKA revision for infection was independently associated with complications (odds ratio [OR], 3.736; 95% confidence interval [CI], 3.198-4.365; p < 0.001), 30-day readmission (OR, 1.455; 95% CI, 1.207-1.755; p < 0.001), 30-day reoperation (OR, 1.614; 95% CI, 1.278-2.037; p < 0.001), and 30-day mortality (OR, 3.337; 95% CI, 1.213-9.180; p = 0.020). Patients with infected TKA had higher rates of postoperative infection (OR, 3.818; 95% CI, 3.082-4.728; p < 0.001), renal failure (OR, 36.709; 95% CI, 8.255-163.231; p < 0.001), sepsis (OR, 7.582; 95% CI, 5.529-10.397; p < 0.001), and septic shock (OR, 3.031; 95% CI, 1.376-6.675; p = 0.006).

CONCLUSIONS

Policymakers should be aware of the higher rate of mortality, readmissions, reoperations, and complications in patients with infected TKA. Without appropriate risk adjustment or excluding these patients all together from alternative payment and quality reporting models, fewer providers will be incentivized to care for patients with infected TKA.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

2015 年《平价医疗法案》和儿童健康保险计划再授权法案为基于结果指标向提供者提供报销提供了框架。人们担心,对因感染而接受翻修 TKA 的患者缺乏风险调整,可能会导致获得护理的问题。

问题/目的:(1)在控制混杂变量后,因感染而接受翻修 TKA 的患者与因无菌原因接受翻修 TKA 的患者相比,30 天再入院、再次手术和死亡率是否更高?(2)与被认为没有感染的接受翻修 TKA 的患者相比,因感染而接受翻修 TKA 的患者发生并发症的风险是否更高?

方法

我们通过美国外科医师学会国家手术质量改进计划数据库,根据当前程序术语(CPT)代码 27486、27487 和 27488 检索 2012 年至 2015 年接受翻修 TKA 的患者。在确定的 10848 名患者中,排除了 4 名患有恶性肿瘤的患者(国际疾病分类,第 9 版代码 170.7、170.9、171.8 或 198.5)。该经过验证的全国性数据库记录了住院手术的短期结果数据,不依赖于行政编码数据。比较了被认为患有感染性 TKA 的患者和因无菌原因接受翻修的患者之间的人口统计学变量、合并症和结果。采用多变量逻辑回归分析确定与并发症、再入院、再次手术和死亡相关的独立因素。

结果

在控制了人口统计学因素和医疗合并症后,TKA 翻修感染与并发症(比值比[OR],3.736;95%置信区间[CI],3.198-4.365;p<0.001)、30 天再入院(OR,1.455;95%CI,1.207-1.755;p<0.001)、30 天再次手术(OR,1.614;95%CI,1.278-2.037;p<0.001)和 30 天死亡率(OR,3.337;95%CI,1.213-9.180;p=0.020)独立相关。感染性 TKA 患者术后感染(OR,3.818;95%CI,3.082-4.728;p<0.001)、肾衰竭(OR,36.709;95%CI,8.255-163.231;p<0.001)、败血症(OR,7.582;95%CI,5.529-10.397;p<0.001)和感染性休克(OR,3.031;95%CI,1.376-6.675;p=0.006)的发生率更高。

结论

决策者应该意识到感染性 TKA 患者的死亡率、再入院率、再次手术率和并发症发生率更高。如果没有适当的风险调整或完全排除这些患者参与替代支付和质量报告模型,那么愿意为感染性 TKA 患者提供治疗的提供者就会减少。

证据等级

三级,治疗性研究。

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