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[甲状旁腺功能减退症和假性甲状旁腺功能减退症。发病机制、诊断和治疗的新进展]

[Hypoparathyroidism and pseudohypoparathyroidism. New aspects of the pathogenesis, diagnosis and therapy].

作者信息

Kruse K

机构信息

Universitäts-Kinderklinik, Würzburg.

出版信息

Monatsschr Kinderheilkd. 1988 Oct;136(10):652-66.

PMID:3070358
Abstract

Recent elucidations of normal and disturbed parathyroid secretion and action have provided a basis for the understanding of general principles of endocrinology. Advanced laboratory methods and simplified study protocols have improved the diagnosis of hypoparathyroidism and pseudohypoparathyroidism, the most important feature of which is chronic hypocalcemia. The knowledge of these disorders is of great importance to the pediatrician since they occur in childhood, and the consequences of prolonged misdiagnosis and inadequate treatment may be serious.

摘要

近期对甲状旁腺正常及紊乱分泌与作用的阐明为理解内分泌学的一般原理提供了基础。先进的实验室方法和简化的研究方案改善了甲状旁腺功能减退症和假性甲状旁腺功能减退症的诊断,其最重要的特征是慢性低钙血症。这些疾病的知识对儿科医生非常重要,因为它们发生在儿童期,长期误诊和治疗不当的后果可能很严重。

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