儿童癌症病史相关的性腺功能减退症：内分泌管理与随访。
Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up.
机构信息
Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, UMCU, Utrecht, The Netherlands,
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands,
出版信息
Horm Res Paediatr. 2019;91(2):93-103. doi: 10.1159/000495943. Epub 2019 Jan 31.
Abstract
Hypogonadism after treatment for childhood cancer is a recognized complication and its cause may be subdivided into primary gonadal failure and central hypogonadism. Here, we provide an overview of the risk factors for the development of hypogonadism, assessment and potential interventions and give a summary of the current recommendations for management and follow-up of hypogonadism in childhood cancer survivors.
摘要
儿童癌症治疗后出现性腺功能减退症是一种公认的并发症，其病因可分为原发性性腺功能衰竭和中枢性性腺功能减退症。在这里，我们概述了性腺功能减退症发展的危险因素、评估和潜在干预措施，并总结了目前对儿童癌症幸存者性腺功能减退症管理和随访的建议。
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