Jaup B H
Department of Medicine, Lundby Hospital, University of Göteborg, Sweden.
Pharmacology. 1988;37 Suppl 1:4-10. doi: 10.1159/000138499.
The purpose of this review is to examine the role of vagal influence on the regulation of gastric acid secretion in humans, and to answer the question as to whether there is any indication of increased vagal tonus being involved in the pathogenesis of peptic ulcers. Apart from the central importance of vagal influence on gastric acid secretion, there is no direct evidence for the existence of general vagal hyperactivity in peptic ulcer patients. Increased vagal activity can only be indirectly demonstrated for a subgroup of duodenal ulcer patients. The involvement of psychodynamic factors as a background phenomenon is emphasized.
本综述的目的是研究迷走神经对人类胃酸分泌调节的作用，并回答是否有迹象表明迷走神经张力增加参与消化性溃疡发病机制的问题。除了迷走神经对胃酸分泌的核心重要性外，尚无直接证据表明消化性溃疡患者存在普遍的迷走神经功能亢进。仅能间接证明一部分十二指肠溃疡患者存在迷走神经活动增加。文中强调了心理动力学因素作为背景现象的参与情况。
