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上颌窦和颊黏膜低度恶性肌纤维母细胞肉瘤:两例罕见病例及文献复习

Low-grade myofibroblastic sarcoma of maxillary sinus and buccal mucosa: Two rare cases and review of the literature.

作者信息

Ghosh Anirban, Bandopadhyay Arghya, Sarkar Rajarshi

机构信息

Department of ENT, MGM Medical College, Kishanganj, Bihar, India.

Department of Pathology, Burdwan Medical College, Kolkata, West Bengal, India.

出版信息

Indian J Pathol Microbiol. 2019 Jan-Mar;62(1):119-121. doi: 10.4103/IJPM.IJPM_99_18.

Abstract

Low-grade myofibroblastic sarcoma (LGMS) represents an atypical tumor composed of myofibroblasts with a predilection for the head and neck, especially in the tongue and oral cavity, with a high tendency to local recurrence and metastasis, even after a long period. LGMS arising from maxillary sinus and buccal mucosa are not very common. To the best of our knowledge, only 55 cases of low-grade myofibroblastic sarcoma have been reported and only four cases of LGMS of maxillary sinus and three cases of LGMS of buccal mucosa have been reported in world literature. We report two cases of LGMS of the maxillary sinus and buccal mucosa, discussing clinical, histological, inmunohistochemical and therapeutic features.

摘要

低级别肌纤维母细胞肉瘤(LGMS)是一种由肌纤维母细胞组成的非典型肿瘤,好发于头颈部,尤其是舌部和口腔,即使经过很长时间,仍有较高的局部复发和转移倾向。起源于上颌窦和颊黏膜的LGMS并不常见。据我们所知,世界文献中仅报道了55例低级别肌纤维母细胞肉瘤,其中仅4例上颌窦LGMS和3例颊黏膜LGMS。我们报告2例上颌窦和颊黏膜LGMS病例,并讨论其临床、组织学、免疫组化及治疗特点。

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