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Meizothrombin, a major product of factor Xa-catalyzed prothrombin activation.

作者信息

Rosing J, Tans G

机构信息

Department of Biochemistry, University of Limburg, Maastricht, The Netherlands.

出版信息

Thromb Haemost. 1988 Dec 22;60(3):355-60.

PMID:3070824
Abstract
摘要

相似文献

1
Meizothrombin, a major product of factor Xa-catalyzed prothrombin activation.中间凝血酶,一种因子Xa催化凝血酶原激活的主要产物。
Thromb Haemost. 1988 Dec 22;60(3):355-60.
2
Formation of meizothrombin as intermediate in factor Xa-catalyzed prothrombin activation on endothelial cells. The influence of thrombin on the reaction mechanism.在内皮细胞上,凝血因子Xa催化凝血酶原激活过程中,中间产物中凝血酶原酶的形成。凝血酶对反应机制的影响。
J Biol Chem. 1991 Feb 25;266(6):4017-22.
3
Formation of meizothrombin as intermediate in factor Xa-catalyzed prothrombin activation.在因子Xa催化的凝血酶原激活过程中,中间产物中凝血酶原酶的形成。
J Biol Chem. 1986 Mar 25;261(9):4224-8.
4
Autocatalytic peptide bond cleavages in prothrombin and meizothrombin.凝血酶原和中凝血酶中的自催化肽键裂解。
Biochemistry. 1998 Feb 3;37(5):1185-91. doi: 10.1021/bi971948h.
5
The prothrombinase-catalyzed activation of prothrombin proceeds through the intermediate meizothrombin in an ordered, sequential reaction.凝血酶原酶催化凝血酶原的激活在一个有序的顺序反应中通过中间产物中凝血酶进行。
J Biol Chem. 1986 Jul 5;261(19):8977-84.
6
Meizothrombin formation during factor Xa-catalyzed prothrombin activation. Formation in a purified system and in plasma.凝血因子Xa催化凝血酶原激活过程中中间凝血酶的形成。在纯化系统和血浆中的形成。
J Biol Chem. 1991 Nov 15;266(32):21864-73.
7
Formation of factor Va by atherosclerotic rabbit aorta mediates factor Xa-catalyzed prothrombin activation.动脉粥样硬化兔主动脉生成的因子Va介导因子Xa催化的凝血酶原激活。
J Clin Invest. 1988 Jun;81(6):1911-9. doi: 10.1172/JCI113538.
8
Neutralization of heparin by prothrombin activation products.凝血酶原激活产物对肝素的中和作用。
Thromb Res. 1987 Mar 1;45(5):573-80. doi: 10.1016/0049-3848(87)90320-3.
9
Characterization of a stable form of human meizothrombin derived from recombinant prothrombin (R155A, R271A, and R284A).源自重组凝血酶原(R155A、R271A和R284A)的人凝血酶原稳定形式的特性分析。
J Biol Chem. 1994 Apr 15;269(15):11374-80.
10
Three aspects of prothrombin activation related to protein M, ecarin, acutin, meizothrombin 1 and prethrombin 2.
Ann N Y Acad Sci. 1981;370:453-67. doi: 10.1111/j.1749-6632.1981.tb29756.x.

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Modeling Thrombin Generation in Plasma under Diffusion and Flow.在扩散和流动条件下的血浆中凝血酶生成的建模。
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Enhancing the anticoagulant profile of meizothrombin.增强凝血酶原复合物的抗凝特性。
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Membrane binding by prothrombin mediates its constrained presentation to prothrombinase for cleavage.凝血酶原与膜的结合介导了其向凝血酶原酶的受限呈递以进行裂解。
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Regulated cleavage of prothrombin by prothrombinase: repositioning a cleavage site reveals the unique kinetic behavior of the action of prothrombinase on its compound substrate.受调控的凝血酶原的酶切:重新定位酶切位点揭示了凝血酶原酶对其复合底物作用的独特动力学行为。
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Expression of allosteric linkage between the sodium ion binding site and exosite I of thrombin during prothrombin activation.凝血酶原激活过程中钠离子结合位点与凝血酶外部位I之间变构连接的表达。
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The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.未结合配体的牛α-凝血酶与凝血酶原-2的共晶体结构:配体结合后Tyr-Pro-Pro-Trp片段和活性位点残基的移动
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Comparison of the active-site conformations of bovine alpha-thrombin and meizothrombin(desF1) by electron spin resonance.通过电子自旋共振比较牛α-凝血酶和美佐凝血酶(去F1)的活性位点构象。
J Protein Chem. 1996 Feb;15(2):231-42. doi: 10.1007/BF01887403.