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[环孢素A使用经验报告]

[Report of experiences on the use of cyclosporin A].

作者信息

Konert J, Eismann R, Heinrichs H J, Langkopf B

机构信息

Urologischen Klinik und Poliklinik, Martin-Luther-Universität Halle-Wittenberg.

出版信息

Z Gesamte Inn Med. 1988 Sep 1;43(17):477-9.

PMID:3070973
Abstract

In September 1985 in our kidney transplantation centre for the first time ciclosporin A was used. Up to now altogether 50 patients received this new form of immunosuppression. During the sand immune application no essential side effects occurred. The success of the change of the therapy was independent of the degree of the serum creatinine level at the time of conversion. In the period of observation we performed altogether 106 kidney transplantations. With 88% of grafts functioning normally at the discharge under application of ciclosporin A we achieved a clear improvement of the results of transplantation in comparison with the classical immunosuppression (53.6%) in the period of observation.

摘要

1985年9月,我们的肾脏移植中心首次使用环孢素A。到目前为止,共有50名患者接受了这种新的免疫抑制形式。在应用期间未出现严重副作用。治疗改变的成功与否与转换时血清肌酐水平的程度无关。在观察期内,我们共进行了106例肾脏移植手术。与观察期内经典免疫抑制(53.6%)相比,在应用环孢素A的情况下,88%的移植肾在出院时功能正常,我们实现了移植结果的明显改善。

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