Röcken M
Dermatologische und Allergologische Abteilung des Städtischen Krankenhauses München-Schwabing, Universität München.
Z Hautkr. 1988 Nov 15;63(11):911-4.
Although lichen planus (LP) is still considered a disease of unknown origin, we succeeded in developing a synoptic pathogenetic concept based on the various scientific studies in this field, which may supply a rational foundation for the empirically established therapy. Genetic and metabolic factors predispose to the development of LP, which can be viewed as a type-IV reaction against immunologically altered keratinocytes. The papule is the result of exaggerated repair mechanisms.
尽管扁平苔藓（LP）仍被认为是一种病因不明的疾病，但我们基于该领域的各种科学研究成功地建立了一个概要性的发病机制概念，这可能为经验性确立的治疗提供合理依据。遗传和代谢因素易导致LP的发生，LP可被视为针对免疫改变的角质形成细胞的IV型反应。丘疹是过度修复机制的结果。
