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白塞病患者的光学相干断层扫描血管造影结果

Optical coherence tomography angiography findings in Behcet patients.

作者信息

Emre Sinan, Güven-Yılmaz Suzan, Ulusoy Mahmut Oğuz, Ateş Halil

机构信息

Department of Ophthalmology, Başkent University School of Medicine Zübeyde Hanım Research Hospital, İzmir, Turkey.

Department of Ophthalmology, Ege University School of Medicine, İzmir, Turkey.

出版信息

Int Ophthalmol. 2019 Oct;39(10):2391-2399. doi: 10.1007/s10792-019-01080-1. Epub 2019 Feb 1.

DOI:10.1007/s10792-019-01080-1
PMID:30710254
Abstract

PURPOSE

Retinal vasculitis and vein occlusions are common causes of serious visual loss in Behçet's disease. We aimed to evaluate the optical coherence tomography angiography (OCTA) findings of Behcet uveitis (BU) patients.

METHODS

We evaluated 32 eyes of 16 patients with BU and 30 eyes of 15 healthy controls. Superficial capillary plexus (SCP) and deeper capillary plexuses (DCP) were evaluated using OCTA RTVue XR AVANTI.

RESULTS

On SCP, nonperfusion/hypoperfusion areas (NPA) were seen in 10 eyes, perifoveal capillary arcade disruption (PCAD) was seen in 10 eyes, capillary network disorganization (CND) was seen in 7 eyes and intraretinal cystoid spaces (ICS) were seen in 2 eyes. On DCP, NPA were seen in 13 eyes, PCAD was seen in 11 eyes, CND was seen in 7 eyes and ICS were seen in 4 eyes.

CONCLUSION

We showed that DCP were affected more than SCP in these patients. In addition, capillary vessel density of BU group was significantly lower than control group.

摘要

目的

视网膜血管炎和静脉阻塞是白塞病导致严重视力丧失的常见原因。我们旨在评估白塞葡萄膜炎(BU)患者的光学相干断层扫描血管造影(OCTA)结果。

方法

我们评估了16例BU患者的32只眼以及15名健康对照者的30只眼。使用OCTA RTVue XR AVANTI评估浅表毛细血管丛(SCP)和深层毛细血管丛(DCP)。

结果

在SCP上,10只眼可见无灌注/低灌注区(NPA),10只眼可见黄斑周围毛细血管弓破坏(PCAD),7只眼可见毛细血管网络紊乱(CND),2只眼可见视网膜内囊样间隙(ICS)。在DCP上,13只眼可见NPA,11只眼可见PCAD,7只眼可见CND,4只眼可见ICS。

结论

我们表明,在这些患者中DCP比SCP受影响更大。此外,BU组的毛细血管密度明显低于对照组。

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J Ophthalmol. 2017;2017:2180723. doi: 10.1155/2017/2180723. Epub 2017 May 9.
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Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):190-196. doi: 10.1167/iovs.16-20531.
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