Gruber R, Peter R, Hora J
Department of Pediatric Surgery, University Hospital Basel, Switzerland.
Z Kinderchir. 1988 Dec;43(6):375-83. doi: 10.1055/s-2008-1043488.
The experience acquired during 10 years treatment of 33 children having undergone a large craniectomy with an average follow-up time of 5.3 years is presented. Different methods of primary and delayed closure of the skull defect are documented and discussed. Whenever possible the deep frozen conserved skull flap was reimplanted. The problem of skull flap resorption and insufficient spontaneous ossification and the alternative of a heterologous cranioplasty with methylmethacrylate (MMA) in cases of insufficient reossification is considered. The decision to use MMA as a secondary skull defect graft should be delayed at least one year after craniectomy, since a spontaneous reossification of the defect is possible until adolescence.
本文介绍了对33例接受大型颅骨切除术的儿童进行10年治疗的经验，平均随访时间为5.3年。记录并讨论了颅骨缺损一期和延期闭合的不同方法。只要有可能，就重新植入深冻保存的颅骨瓣。考虑了颅骨瓣吸收、自发性骨化不足的问题，以及在骨化不足的情况下采用甲基丙烯酸甲酯（MMA）进行异体颅骨成形术的替代方法。使用MMA作为继发性颅骨缺损移植物的决定应在颅骨切除术后至少推迟一年，因为在青春期之前缺损有可能自发骨化。
