Dadoo Ahmed S, Steenkamp Ilana
Department of Dermatology, Kimberley Hospital Complex, Kimberley, Northern Cape.
Dermatol Online J. 2019 Jan 15;25(1):13030/qt6sr7c44c.
A 44-year-old man known to have human immunodeficiency virus (HIV) infection presented to our clinic with erythroderma, generalized lymphadenopathy, and cutaneous nodules and tumors. After a series of investigations, we confirmed that he had Sézary syndrome. In this paper we describe the immune alterations that occur in both Sézary Syndrome and HIV infection and how these changes together resulted in rapid and overwhelming immune dysregulation in our patient.
一名已知感染人类免疫缺陷病毒(HIV)的44岁男性因红皮病、全身淋巴结肿大以及皮肤结节和肿瘤前来我院就诊。经过一系列检查,我们确诊他患有塞扎里综合征。在本文中,我们描述了塞扎里综合征和HIV感染中发生的免疫改变,以及这些变化如何共同导致我们这位患者出现快速且严重的免疫失调。