Evans M I, Zador I E, Qureshi F, Budev H, Quigg M H, Nadler H L
Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Michigan 48201.
Am J Med Genet. 1988 Dec;31(4):915-20. doi: 10.1002/ajmg.1320310426.
In a family at risk for Langer mesomelic dwarfism, we document the onset of disproportionate growth in the second trimester by sonographic biometry. Midtrimester pathologic correlation of this condition demonstrates primary changes in the growthplate in the regions of proliferating cartilage and hypertrophic and degenerative chondrocytes.
