Ludwig R, Oppermann H C, Geiger H, Willich E
Monatsschr Kinderheilkd (1902). 1978 Jun;126(6):401-4.
During the early phase of their disease three children with acute lymphoblastic leukemia showed unusual skeletal changes radiologically. Mainly osteolysis in the lower jaw, opacity of the sinus, decreased hight of the vertebrae, and a unilateral necrosis of the head of the femur. These skeletal alterations are much more common in other diseases than in acute lymphoblastic leukemia.
在疾病早期,三名急性淋巴细胞白血病患儿的骨骼在放射学上呈现出异常变化。主要表现为下颌骨骨质溶解、鼻窦浑浊、椎体高度降低以及单侧股骨头坏死。这些骨骼改变在其他疾病中比在急性淋巴细胞白血病中更为常见。