县家庭收入中位数是IV期间变性甲状腺癌的独立预后因素。
County Median Family Income Is an Independent Prognostic Factor for Stage IV Anaplastic Thyroid Cancer.
作者信息
Li M U, Gu Sophi, Mao Rui, Ning Ying, Trivedi Nitin, Siddiqui Ahmad, Li Pengyang, Huo Lihong
机构信息
Department of Internal Medicine, St Vincent Hospital, Worcester, MA, U.S.A.
M.D. Program, Johns Hopkins University School of Medicine, Baltimore, MA, U.S.A.
出版信息
Anticancer Res. 2019 Feb;39(2):949-956. doi: 10.21873/anticanres.13198.
BACKGROUND/AIM: Advanced anaplastic thyroid cancer (ATC) is a rare, but highly aggressive malignancy, and its prognostic factors need to be further explored. We examined socioeconomic factors' predictive effect for survival performance in stage IV ATC patients.
MATERIALS AND METHODS
Using the Surveillance, Epidemiology, and End Results database, we collected 1,048 cases with stage IV anaplastic thyroid cancer (ATC) from 2004 to 2015. Demographic, clinical, and socioeconomic factors were evaluated using univariate and multivariate analyses.
RESULTS
Median family income showed a significant effect on overall survival (OS) and cancer-specific survival (CSS) in univariate analysis. Median family income level was found to be an independent prognostic factor for OS after multivariate adjustment Multivariate analysis for CSS showed similar results.
CONCLUSION
Family income level is an independent prognostic factor for stage IV ATC.
背景/目的：晚期间变性甲状腺癌（ATC）是一种罕见但侵袭性很强的恶性肿瘤，其预后因素有待进一步探索。我们研究了社会经济因素对IV期ATC患者生存表现的预测作用。
材料与方法
利用监测、流行病学和最终结果数据库，我们收集了2004年至2015年期间1048例IV期间变性甲状腺癌（ATC）病例。通过单因素和多因素分析评估人口统计学、临床和社会经济因素。
结果
单因素分析显示，家庭收入中位数对总生存期（OS）和癌症特异性生存期（CSS）有显著影响。多因素调整后发现家庭收入中位数水平是OS的独立预后因素。CSS的多因素分析显示了类似结果。
结论
家庭收入水平是IV期ATC的独立预后因素。
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