食管癌切除术后肺炎与全身炎症反应综合征
Postoperative Pneumonia After Esophagectomy and Systemic Inflammatory Response Syndrome.
作者信息
Asaka Shinichi, Shimakawa Takeshi, Yamaguchi Kentaro, Katsube Takao, Usui Takebumi, Yokomizo Hajime, Shiozawa Shunichi, Naritaka Yoshihiko
机构信息
Department of Surgery, Tokyo Women's Medical University Medical Center East, Tokyo, Japan
Department of Surgery, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.
出版信息
Anticancer Res. 2019 Feb;39(2):979-985. doi: 10.21873/anticanres.13202.
BACKGROUND/AIM: The aim of this study was to determine the association between post-esophagectomy pneumonia and the presence of pathogenic organisms in the sputum or pharynx and postoperative systemic inflammatory response syndrome (SIRS).
MATERIALS AND METHODS
This retrospective study included 98 patients diagnosed with esophageal cancer who had undergone esophagectomy.
RESULTS
Postoperative pneumonia was observed in 24 patients (24.5%). Of the total 98 patients, 45 (45.9%) were tested positive for pathogenic organisms preoperatively, and 16 of those (35.6%) developed postoperative pneumonia; postoperative pneumonia occurred at a higher rate in these patients compared to pathogenic organism-negative patients (p=0.019). Postoperative SIRS was observed in 62 patients (63.3%), and 21 of these (33.9%) developed postoperative pneumonia, a significantly higher rate compared to patients without SIRS (p=0.007).
CONCLUSION
Postoperative pneumonia was significantly associated with the presence of pathogenic organisms in the sputum or pharynx and postoperative SIRS.
背景/目的：本研究旨在确定食管癌切除术后肺炎与痰液或咽部致病微生物的存在以及术后全身炎症反应综合征（SIRS）之间的关联。
材料与方法
这项回顾性研究纳入了98例诊断为食管癌并接受了食管切除术的患者。
结果
24例患者（24.5%）发生了术后肺炎。在总共98例患者中，45例（45.9%）术前致病微生物检测呈阳性，其中16例（35.6%）发生了术后肺炎；与致病微生物阴性的患者相比，这些患者术后肺炎的发生率更高（p=0.019）。62例患者（63.3%）出现了术后SIRS，其中21例（33.9%）发生了术后肺炎，与未发生SIRS的患者相比，发生率显著更高（p=0.007）。
结论
术后肺炎与痰液或咽部致病微生物的存在以及术后SIRS显著相关。
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