Navarro-Hernández E, Hernández-Pons A, Montolío-Marzo S, Pérez-López M
Servicio de Oftalmología, Hospital Virgen de los Lirios, Alcoy, Alicante, España.
Servicio de Oftalmología, Hospital Universitario Dr. Peset, Valencia, España.
Arch Soc Esp Oftalmol (Engl Ed). 2019 May;94(5):248-251. doi: 10.1016/j.oftal.2018.12.004. Epub 2019 Feb 1.
Orbital adult-onset xanthogranuloma is a rare idiopathic inflammatory disorder included in the group of orbital xanthogranulomatous diseases with possible systemic associations. A 43 year-old woman presented with a deep fast-growing mass on the right upper eyelid. She had a past medical history of bilateral non-ulcerative nodules on the upper eyelid and two cosmetic upper lid blepharoplasties. An excisional biopsy was performed and the histopathology analysis confirmed the diagnosis of adult histiocytic xanthogranuloma. The systemic work up was negative and the patient is asymptomatic without treatment. Orbital xanthogranulomatous diseases are rare, but potentially life-threatening disorders. The ophthalmologist must be aware of this disease in order to make an early diagnosis using the anamnesis, clinical examination, and histology of the periocular lesions that may resemble palpebral xanthelasmas.
眼眶成人起病性黄色瘤是一种罕见的特发性炎症性疾病，属于眼眶黄色瘤病组，可能存在全身关联。一名43岁女性患者右上眼睑出现一个深部快速生长的肿块。她既往有双侧上眼睑非溃疡性结节病史，曾接受过两次上睑整形美容手术。进行了切除活检，组织病理学分析确诊为成人组织细胞性黄色瘤。全身检查结果为阴性，患者未经治疗无症状。眼眶黄色瘤病罕见，但可能危及生命。眼科医生必须了解这种疾病，以便通过病史、临床检查以及可能类似睑黄瘤的眼周病变组织学检查进行早期诊断。
