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应用扫频源光学相干断层扫描技术检测牙釉质表面下的病变。

Detection of enamel subsurface lesions by swept-source optical coherence tomography.

机构信息

Division of Aesthetic Dentistry and Clinical Cariology, Department of Conservative Dentistry, Showa University School of Dentistry.

Division of Biomaterials and Engineering, Department of Conservative Dentistry, Showa University School of Dentistry.

出版信息

Dent Mater J. 2019 Mar 31;38(2):303-310. doi: 10.4012/dmj.2017-404. Epub 2019 Feb 1.

Abstract

This study aimed to non-destructively analyze the progression of subsurface enamel caries using swept-source optical coherence tomography (SS-OCT), a recently developed imaging analysis modality. Artificial enamel caries at various stages of demineralization were created in bovine tooth enamel using a modified lactic acid gel system. Untreated enamel served as a control. OCT images from cross-sections of enamel were collected. Mineral density, distribution, and histological changes were analyzed using an electron probe microanalyzer, scanning electron microscopy, and contact microradiography. The Raman spectrum and X-ray structural analysis of the enamel surfaces were determined. SS-OCT detected significant differences in mineral loss among the samples. A high-brightness image was confirmed, along with changes in the respective brightness graphs proportionate to the degree of demineralization. SS-OCT can potentially be used to evaluate the progression of incipient enamel carious lesions.

摘要

本研究旨在利用最新发展的成像分析模式——扫频源光学相干断层扫描(SS-OCT),对牙釉质表面下龋病的进展进行无损分析。使用改良乳酸凝胶系统,在牛牙釉质上人为制造处于不同脱矿阶段的牙釉质龋。未处理的牙釉质作为对照。采集牙釉质横断面的 OCT 图像。利用电子探针微分析、扫描电子显微镜和接触显微放射摄影术对矿物质密度、分布和组织学变化进行分析。同时还测定了牙釉质表面的拉曼光谱和 X 射线结构分析。SS-OCT 检测到样本间矿物质损失的显著差异。证实了高亮度图像,并观察到各自亮度图谱随脱矿程度成比例的变化。SS-OCT 有望用于评估早期釉质龋损的进展。

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