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非动脉瘤性蛛网膜下腔出血:多系统萎缩患者罕见的死亡原因

Non-aneurysmal Subarachnoid Hemorrhaging: A Rare Cause of Death in a Patient with Multiple System Atrophy.

作者信息

Kinoshita Hisanori, Ayaki Takashi, Maki Takakuni, Goda Naoki, Yoshizawa Akihiko, Takahashi Ryosuke

机构信息

Department of Neurology, Kyoto University Graduate School of Medicine, Japan.

Department of Diagnostic Pathology, Kyoto University Hospital, Japan.

出版信息

Intern Med. 2019 Jun 1;58(11):1643-1644. doi: 10.2169/internalmedicine.1567-18. Epub 2019 Feb 1.

Abstract

Sudden death as a result of multiple system atrophy (MSA) is usually attributed to vocal cord paralysis or disruption of breathing owing to the degeneration of the brainstem respiratory centers. However, the exact pathophysiology of sudden death is still unclear. In addition, specific causes of sudden death are not always investigated by an autopsy. We herein report a patient with MSA and non-aneurysmal subarachnoid hemorrhaging, which is believed to be a rare cause of death in this setting. Without an autopsy, our case would likely have been diagnosed as sudden death due to vocal cord paralysis. To develop effective strategies to prevent sudden death, a post-mortem investigation is important in order to exclude known structural causes of death.

摘要

多系统萎缩(MSA)导致的猝死通常归因于声带麻痹或由于脑干呼吸中枢退化引起的呼吸中断。然而,猝死的确切病理生理学仍不清楚。此外,猝死的具体原因并不总是通过尸检来调查。我们在此报告一例患有MSA并伴有非动脉瘤性蛛网膜下腔出血的患者,这被认为是这种情况下罕见的死亡原因。如果没有尸检,我们的病例很可能会被诊断为因声带麻痹导致的猝死。为了制定有效的预防猝死策略,死后调查对于排除已知的结构性死亡原因很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/006e/6599920/5851021e85ff/1349-7235-58-1643-g001.jpg

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