探索硬币金属酸盐在三氟甲基化反应中的作用：一项实验与理论相结合的研究
Exploring the Role of Coinage Metalates in Trifluoromethylation: A Combined Experimental and Theoretical Study.
作者信息
Martínez de Salinas Sara, Mudarra Ángel L, Odena Carlota, Martínez Belmonte Marta, Benet-Buchholz Jordi, Maseras Feliu, Pérez-Temprano Mónica H
机构信息
Institute of Chemical Research of Catalonia (ICIQ), Avgda. Països Catalans 16, 43007, Tarragona, Spain.
Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, C/ Marcelli Domingo s/n, 43007, Tarragona, Spain.
出版信息
Chemistry. 2019 Jul 17;25(40):9390-9394. doi: 10.1002/chem.201900496. Epub 2019 Mar 26.
Despite the known nucleophilic nature of [M(CF ) ] (M=Cu, Ag, Au) complexes, their participation in trifluoromethylation reactions of aryl halides remains unexplored. Here, for the first time, selective access to a [Cu(CF ) ] species is reported, which is ubiquitous in Cu-mediated trifluoromethylations, and we rationalize its complex mechanistic scenario as well as its behavior compared to its silver and gold congeners through a combination of experimental and computational approaches.
尽管已知[M(CF₃)ₓ]（M = Cu、Ag、Au）配合物具有亲核性质，但它们在芳基卤化物的三氟甲基化反应中的参与情况仍未得到探索。在此，首次报道了一种在铜介导的三氟甲基化反应中普遍存在的[Cu(CF₃)ₓ]物种，并且我们通过实验和计算方法相结合，阐明了其复杂的反应机理以及与银和金同族物相比的行为。
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