Maduna Liteboho D, Laumen Jolein Ge, Radebe Oscar, Kock Marleen M, Peters Remco Ph
1 Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa.
2 Department of Medical Microbiology, School of Public Health & Primary Care (CAPHRI), Maastricht University Medical Centre, Maastricht, The Netherlands.
Int J STD AIDS. 2019 Apr;30(5):519-521. doi: 10.1177/0956462418820745. Epub 2019 Feb 4.
We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. genitalium infection can undermine the effectiveness of syndromic management in Africa.
我们报告了南非一例因对大环内酯类耐药的生殖支原体导致男性尿道炎综合征治疗失败的病例。我们检测到23S核糖体RNA及一个喹诺酮耐药决定区发生了突变。本报告证实，耐药的生殖支原体感染会削弱非洲综合征管理的有效性。
