Gelardi Matteo, Intiglietta Pierluigi, Porro Giuseppe, Quaranta Vitaliano Nicola, Resta Onofrio, Quaranta Nicola, Ciprandi Giorgio
Otolaryngology Unit, Department of Basic Medical Science, Neuroscience and Sensory Organs, University of Bari, Italy.
Acta Biomed. 2019 Jan 11;90(2-S):19-23. doi: 10.23750/abm.v90i2-S.8099.
The nasal valve area has the minimal cross-sectional area of the upper airways. Obstructive sleep apnea (OSA) is a common disorder. It has been reported that nasal obstruction may be associated with OSA. The aim of this study was to investigate whether the use an internal nasal dilator may be able to affect respiratory pattern in a group of patients with OSA. The use of internal nasal dilator was able to significantly reduce two relevant respiratory outcomes, such as the apnea-hypopnea index and the oxygen desaturation index, notably there was also a positive trend for the reduction of total sleep time with HbO2 <90%). Nas-air® was also able to significantly improve restorative sleep performance. In conclusion, the present study demonstrates that Nas-air® is a new internal nasal dilator potentially capable to significantly improve respiratory outcomes and sleep quality.
鼻瓣区是上呼吸道中横截面积最小的部位。阻塞性睡眠呼吸暂停（OSA）是一种常见疾病。据报道，鼻阻塞可能与OSA有关。本研究的目的是调查使用鼻内扩张器是否能够影响一组OSA患者的呼吸模式。使用鼻内扩张器能够显著降低两个相关的呼吸指标，如呼吸暂停低通气指数和氧饱和度下降指数，值得注意的是，在总睡眠时间中血红蛋白氧饱和度<90%的时间减少方面也有积极趋势。Nas-air®还能够显著改善恢复性睡眠表现。总之，本研究表明Nas-air®是一种新型鼻内扩张器，有可能显著改善呼吸指标和睡眠质量。
