阻塞性睡眠呼吸暂停综合征患者使用持续气道正压通气治疗时的鼻内扩张器

Internal nasal dilator in patients with obstructive sleep apnea syndrome and treated with continuous positive airway pressure.

作者信息

Gelardi Matteo, Intiglietta Pierluigi, Porro Giuseppe, Quaranta Vitaliano Nicola, Resta Onofrio, Quaranta Nicola, Ciprandi Giorgio

机构信息

Otolaryngology Unit, Department of Basic Medical Science, Neuroscience and Sensory Organs, University of Bari, Italy.

出版信息

Acta Biomed. 2019 Jan 11;90(2-S):24-7. doi: 10.23750/abm.v90i2-S.8100.

DOI:10.23750/abm.v90i2-S.8100

PMID:30715034

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6502073/

Abstract

The nasal valve area has the minimal cross-sectional area of the upper airways. Obstructive sleep apnea syndrome (OSAS) is a common disorder. It has been reported that nasal obstruction may be associated with OSAS. The aim of this study was to investigate whether the use an internal nasal dilator may be able to affect respiratory pattern in a group of patients with OSAS and treated with continuous positive airway pressure (CPAP). The use of internal nasal dilator significantly reduced the pressure of CPAP (from 11.4±1.5 to 10.8±1.5; p=0.012) able to resolve apnea episodes. In conclusion, this study showed that Nas-air® is a new internal nasal dilator potentially capable to significantly improve adherence and compliance to CPAP.

摘要

鼻瓣区是上呼吸道横截面面积最小的部位。阻塞性睡眠呼吸暂停综合征（OSAS）是一种常见疾病。据报道，鼻塞可能与OSAS有关。本研究的目的是调查使用鼻内扩张器是否能够影响一组接受持续气道正压通气（CPAP）治疗的OSAS患者的呼吸模式。使用鼻内扩张器显著降低了能够解决呼吸暂停发作的CPAP压力（从11.4±1.5降至10.8±1.5；p = 0.012）。总之，本研究表明Nas-air®是一种新型鼻内扩张器，有可能显著提高对CPAP的依从性和顺应性。