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光剑透镜 - 一种新型的老视补偿方法:初步临床研究。

The Light Sword Lens - A novel method of presbyopia compensation: Pilot clinical study.

机构信息

Faculty of Physics, Warsaw University of Technology, Warsaw, Poland.

Ophthalmology Department, Military Institute of Medicine, Warsaw, Poland.

出版信息

PLoS One. 2019 Feb 4;14(2):e0211823. doi: 10.1371/journal.pone.0211823. eCollection 2019.

DOI:10.1371/journal.pone.0211823
PMID:30716136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6361462/
Abstract

PURPOSE

Clinical assessment of a new optical element for presbyopia correction-the Light Sword Lens.

METHODS

Healthy dominant eyes of 34 presbyopes were examined for visual performance in 3 trials: reference (with lens for distance correction); stenopeic (distance correction with a pinhole ϕ = 1.25 mm) and Light Sword Lens (distance correction with a Light Sword Lens). In each trial, visual acuity was assessed in 7 tasks for defocus from 0.2D to 3.0D while contrast sensitivity in 2 tasks for defocus 0.3D and 2.5D. The Early Treatment Diabetic Retinopathy Study protocol and Pelli-Robson method were applied. Within visual acuity and contrast sensitivity results degree of homogeneity through defocus was determined. Reference and stenopeic trials were compared to Light Sword Lens results. Friedman analysis of variance, Nemenyi post-hoc, Wilcoxon tests were used, p-value < 0.05 was considered significant.

RESULTS

In Light Sword Lens trial visual acuity was stable in tested defocus range [20/25-20/32], Stenopeic trial exhibited a limited range of degradation [20/25-20/40]. Light Sword Lens and reference trials contrast sensitivity was high [1.9-2.0 logCS] for both defocus cases, but low in stenopeic condition [1.5-1.7 logCS]. Between-trials comparisons of visual acuity results showed significant differences only for Light Sword Lens versus reference trials and in contrast sensitivity only for Light Sword Lens versus stenopeic trials.

CONCLUSIONS

Visual acuity achieved with Light Sword Lens correction in presbyopic eye is comparable to stenopeic but exhibits none significant loss in contrast sensitivity. Such correction method seems to be very promising for novel contact lenses and intraocular lenses design.

摘要

目的

临床评估一种新的用于老视矫正的光学元件——光剑透镜。

方法

对 34 名老视患者的主导眼进行了 3 项试验的视觉性能检查:参考(使用远用矫正镜片);针孔(距离校正用 1.25mm 的小孔ϕ)和光剑透镜(距离校正用光剑透镜)。在每一项试验中,在 7 项任务中评估了从 0.2D 到 3.0D 的离焦视力,而在 2 项任务中评估了 0.3D 和 2.5D 的离焦对比敏感度。应用早期糖尿病视网膜病变治疗研究方案和佩里-罗宾逊方法。通过离焦确定了视力和对比敏感度结果的均匀度程度。参考试验和针孔试验与光剑透镜结果进行了比较。采用 Friedman 方差分析、Nemenyi 事后检验、Wilcoxon 检验,p 值<0.05 认为有统计学意义。

结果

在光剑透镜试验中,在测试的离焦范围内(20/25-20/32),视力稳定,针孔试验表现出有限的下降范围(20/25-20/40)。光剑透镜和参考试验的对比敏感度在两种离焦情况下都很高(1.9-2.0 logCS),但在针孔条件下较低(1.5-1.7 logCS)。视力结果的三项试验之间的比较仅在光剑透镜与参考试验之间以及对比敏感度仅在光剑透镜与针孔试验之间显示出显著差异。

结论

光剑透镜矫正老视眼的视力与针孔相当,但对比敏感度无明显损失。这种矫正方法似乎对新型隐形眼镜和人工晶状体的设计非常有前途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/30ee1256d390/pone.0211823.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/9966b5e50c72/pone.0211823.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/bdb4f79d1333/pone.0211823.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/8b2dc23d5f51/pone.0211823.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/8bf41b3fec5b/pone.0211823.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/1233d8db1701/pone.0211823.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/30ee1256d390/pone.0211823.g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/9966b5e50c72/pone.0211823.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/bdb4f79d1333/pone.0211823.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/8b2dc23d5f51/pone.0211823.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/8bf41b3fec5b/pone.0211823.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/1233d8db1701/pone.0211823.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31c6/6361462/30ee1256d390/pone.0211823.g006.jpg

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