Hennemann H H
MMW Munch Med Wochenschr. 1978 Jun 30;120(26):891-4.
Septicemias, especially those due to gram-negative pathogens, frequently occur in leukemias, malignant lymphomas and other malignant or metabolic diseases leading to inanition. The causes are disturbances of cellular defense and humoral immune defects. The immune reaction can be affected by disordered antibody function. In addition to a disturbance of leukocyte function due to reduction of granulocytes (granulocytopenia) disturbances of leukocyte function also occur with a normal cell count (granulocytopathy) especially under cytostatic therapy. Besides specific antibiotic therapy it is important to improve the defense position of the organism by treating the primary disease and to assess the disordered immune status correctly.
败血症，尤其是由革兰氏阴性病原体引起的败血症，经常发生于白血病、恶性淋巴瘤以及其他导致虚弱的恶性或代谢性疾病中。其病因是细胞防御功能紊乱和体液免疫缺陷。免疫反应会受到抗体功能紊乱的影响。除了因粒细胞减少（粒细胞缺乏症）导致的白细胞功能障碍外，白细胞功能障碍也会在细胞计数正常的情况下出现（粒细胞病），尤其是在细胞抑制疗法的情况下。除了特异性抗生素治疗外，通过治疗原发性疾病来改善机体的防御状况以及正确评估紊乱的免疫状态也很重要。
