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后半规管良性阵发性位置性眩晕非典型眼震16例临床分析

[Clinical analysis for 16 cases with atypical nystagmus of posterior semicircular canal benign paroxysmal positional vertigo].

作者信息

Zhu Z J, Liu Q

机构信息

Department of Otolaryngology Head and Neck Surgery,Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Ji'nan,250001,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Nov;32(22):1687-1690;1695. doi: 10.13201/j.issn.1001-1781.2018.22.001.

DOI:10.13201/j.issn.1001-1781.2018.22.001
PMID:30716795
Abstract

To study clinical features and evaluate the efficacy of manual reduction in treatment of atypical nystagmus in patients with posterior semicircular canal benign paroxysmal positional vertigo(PSC-BPPV). Sixteen cases of atypical nystagmus in patients with PSC-BPPV were retrospectively analyzed. The results were compared with 28 patients of typical nystagmus with PSC-BPPV.All the patients were followed up for 3 months. Statistical data analysis was carried out with SPSS 20.0. Sixteen cases of atypical nystagmus patients with PSC-BPPV included 5 cases of left 31.25%(5/16) and 11 cases of right 68.75%(11/16), 5 patients showed typical nystagmus in the straight-head hanging position and without vertical down-beating in returning to the sitting positions with torsional component pointed to intact side,4 patients showed same nystagmus in hanging position and vertical down-beating in returning to the sitting positions without torsional component, one patient showed nystagmus of vertical up-beating and vertical down-beating in Dix-Hallpike test without torsional component,2 patients showed unobservable nystagmus in Dix-Hallpike test but showed nystagmus of vertical up-beating with torsional component pointed to affected side in the roll test position,4 patients showed nystagmus of vertical down-beating in the straight-head hanging position with torsional component pointed to intact side and reversible direction nystagmus in returning to the sitting positions.One patient's nystagmus time of duration was longer than 1 min,while 15 patients' nystagmus duration were shorter than 1 min.Twenty-eight patients with typical nystagmus in PSC-BPPV nystagmus duration were shorter than 1 min.No patient had been affected bilateral in two groups. All patients received manual reduction treatment according to the nystagmus direction and time of duration. The effective rate after the first day was 62.50%(10/16) in atypical nystagmus patients with PSC-BPPV group and 92.86%(26/28) in typical nystagmus with PSC-BPPV group, the difference was significant(χ²=5.134,=0.015). The total effective rate was 93.75%(15/16)after more than once in atypical group and 100.00%(28/28) in typical group, the difference was not significant(χ²=2.780,=0.095).The numbers of circulation of first success in manual reduction management were(2.76±1.13)times in atypical group and (1.68±0.61)times in typical group.The difference was significant(=4.293,=0.000). The recurrence rate was 18.75% in atypical group and 14.28% in typical group after during follow-up for 6 months, the difference was not significant(χ²=1.681,=0.509). It showed that clinical manifestation with atypical nystagmus in patients with PSC-BPPV was complicated. Some patients' nystagmus could change to typical after treatment.The manual reduction was an effective treatment.The effective rate after first manual reduction was lower than typical group, it's needed more circulation of first success in manual reduction management. The recurrence rate was not significant in two groups.

摘要

研究后半规管良性阵发性位置性眩晕(PSC-BPPV)患者非典型眼震的临床特征并评估手法复位治疗的疗效。回顾性分析16例PSC-BPPV患者的非典型眼震情况。将结果与28例典型眼震的PSC-BPPV患者进行比较。所有患者均随访3个月。采用SPSS 20.0进行统计数据分析。16例PSC-BPPV非典型眼震患者中,左侧5例占31.25%(5/16),右侧11例占68.75%(11/16);5例患者在直头悬垂位表现为典型眼震,回坐位时无垂直向下跳动且扭转成分指向健侧;4例患者悬垂位眼震相同,回坐位时有垂直向下跳动但无扭转成分;1例患者Dix-Hallpike试验表现为垂直向上跳动和垂直向下跳动且无扭转成分;2例患者Dix-Hallpike试验未观察到眼震,但在滚转试验位表现为垂直向上跳动且扭转成分指向患侧;4例患者直头悬垂位有垂直向下跳动且扭转成分指向健侧,回坐位时有可恢复性方向眼震。1例患者眼震持续时间超过1分钟,15例患者眼震持续时间短于1分钟。28例PSC-BPPV典型眼震患者眼震持续时间均短于1分钟。两组均无双侧受累患者。所有患者均根据眼震方向和持续时间接受手法复位治疗。PSC-BPPV非典型眼震患者组第一天治疗有效率为62.50%(10/16),PSC-BPPV典型眼震患者组为92.86%(26/28),差异有统计学意义(χ²=5.134,P=0.015)。非典型组多次复位后总有效率为93.75%(15/16),典型组为100.00%(28/28),差异无统计学意义(χ²=2.780,P=0.095)。手法复位首次成功的循环次数非典型组为(2.76±1.13)次,典型组为(1.68±0.61)次,差异有统计学意义(t=4.293,P=0.000)。随访6个月,非典型组复发率为18.75%,典型组为14.28%,差异无统计学意义(χ²=1.681,P=0.509)。结果表明,PSC-BPPV患者非典型眼震临床表现复杂。部分患者治疗后眼震可转变为典型。手法复位是一种有效的治疗方法。首次手法复位有效率低于典型组患者,需要更多次数的首次成功复位循环。两组复发率差异无统计学意义。

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